Anti-PLA2R antibodies as a prognostic factor in PLA2R-related membranous nephropathy

SA Timmermans, MA Abdul Hamid… - American journal of …, 2015 - karger.com
Background: The natural course of idiopathic membranous nephropathy (MN) varies, as it is
known through favorable outcomes in most patients. However, one third of patients with …

Rituximab-induced depletion of anti-PLA2R autoantibodies predicts response in membranous nephropathy

LH Beck Jr, FC Fervenza, DM Beck… - Journal of the …, 2011 - journals.lww.com
Autoantibodies to the M-type phospholipase A 2 receptor (PLA 2 R) are sensitive and
specific for idiopathic membranous nephropathy. The anti-B cell agent rituximab is a …

Phospholipase A2 receptor (PLA2R1) sequence variants in idiopathic membranous nephropathy

MJH Coenen, JM Hofstra, H Debiec… - Journal of the …, 2013 - journals.lww.com
The M-type receptor for phospholipase A2 (PLA2R1) is the major target antigen in idiopathic
membranous nephropathy (iMN). Our recent genome-wide association study showed that …

An immunofluorescence test for phospholipase-A2-receptor antibodies and its clinical usefulness in patients with membranous glomerulonephritis

E Hoxha, S Harendza, G Zahner… - Nephrology Dialysis …, 2011 - academic.oup.com
Background. The recent finding that phospholipase-A2-receptor antibodies (PLA2R-AB)
may play a role in the development of primary membranous glomerulonephritis (MGN) offers …

PLA2R Antibody Levels and Clinical Outcome in Patients with Membranous Nephropathy and Non-Nephrotic Range Proteinuria under Treatment with Inhibitors of …

E Hoxha, S Harendza, H Pinnschmidt, U Panzer… - PloS one, 2014 - journals.plos.org
Patients with primary membranous nephropathy (MN) who experience spontaneous
remission of proteinuria generally have an excellent outcome without need of …

[HTML][HTML] Differential diagnosis of membranous nephropathy with autoantibodies to phospholipase A2 receptor 1

W Schlumberger, N Hornig, S Lange, C Probst… - Autoimmunity …, 2014 - Elsevier
Membranous nephropathy (MN) accounts for most cases of the nephrotic syndrome in
adults. Recently, studies on the underlying pathomechanisms led to the identification of the …

Anti-PLA₂R antibodies in membranous nephropathy: ready for routine clinical practice?

JM Hofstra, JF Wetzels - The Netherlands journal of medicine, 2012 - europepmc.org
The identification of circulating autoantibodies against the M-type phospholipase A₂
receptor (anti-PLA₂R) in patients with idiopathic membranous nephropathy (iMN) has been …

Antiphospholipase A2 Receptor Autoantibodies: A Comparison of Three Different Immunoassays for the Diagnosis of Idiopathic Membranous Nephropathy

A Behnert, M Schiffer, J Müller-Deile… - Journal of …, 2014 - Wiley Online Library
Background. The recent identification of circulating autoantibodies directed towards the M‐
type phospholipase A2 receptor (PLA2R) has been a major advancement in the serological …

[HTML][HTML] The anti-PLA2R antibody in membranous nephropathy: what we know and what remains a decade after its discovery

AE van de Logt, M Fresquet, JF Wetzels, P Brenchley - Kidney international, 2019 - Elsevier
The discovery in 2009 of the M-type phospholipase A2 receptor (PLA2R) as the primary
target in membranous nephropathy (MN) greatly advanced basic and clinical research …

Autoantibodies against Phospholipase A2 Receptor in Korean Patients with Membranous Nephropathy

YJ Oh, SH Yang, DK Kim, SW Kang, YS Kim - PloS one, 2013 - journals.plos.org
The data were presented in abstract form at the 45th meeting of the American Society of
Nephrology, October 30-November 04 2012, San Diego, CA, USA. Circulating …