Background: Anti-phospholipase A2 receptor antibody (PLA2R-Ab) is useful in diagnosing
idiopathic membranous nephropathy (IMN). We investigated the clinical relevance of PLA2R …

Background: M-type phospholipase A 2 receptor (PLA 2 R) has been identified as the major
target antigen in idiopathic membranous nephropathy (IMN). However, the role of …

Results From a total of 276 patients with positive anti-phospholipase A2 receptor serology,
previously reported patients (n= 33), kidney transplant recipients (n= 9), pediatric patients …

Autoantibody against phospholipase A2 receptor (anti-PLA2R) is a sensitive and specific
biomarker of idiopathic membranous nephropathy (iMN), being found in approximately 70 …

In patients with membranous nephropathy, alkylating agents (cyclophosphamide or
chlorambucil) alone or in combination with steroids achieve remission of nephrotic …

Background Membranous nephropathy (MN) is the leading cause of nephrotic syndrome in
adults. Anti-M-type phospholipase A2 receptor (anti-PLA2R) antibodies are found in most …

Background Antibodies to M-type phospholipase A2 receptor (PLA2R) correlate with clinical
activity of primary membranous nephropathy (PMN). Risk alleles in PLA2R1 and HLA-DQA1 …

Up to 80% of patients with idiopathic membranous nephropathy have non–complement-
fixing IgG4 autoantibodies to the phospholipase A2 receptor (PLA2R). Membranous …

Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults.
Rituximab, a type I anti-CD20 antibody, has been shown to be an effective therapy in …

Kidney biopsy is the gold standard to diagnose membranous nephropathy (MN).
Approximately 70%-80% of patients with primary MN have anti-phospholipase A2 receptor …