Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy

NM Tomas, LH Beck Jr… - … England Journal of …, 2014 - Mass Medical Soc
Background Idiopathic membranous nephropathy is an autoimmune disease. In
approximately 70% of patients, it is associated with autoantibodies against the …

IgG subclass staining in renal biopsies with membranous glomerulonephritis indicates subclass switch during disease progression

CC Huang, A Lehman, A Albawardi, A Satoskar… - Modern …, 2013 - nature.com
Recent breakthrough findings revealed that most patients with idiopathic (primary)
membranous glomerulonephritis have IgG4 antibodies to the phospholipase A2 receptor …

Immunological remission in PLA2R-antibody–associated membranous nephropathy: cyclophosphamide versus rituximab

AE van de Logt, K Dahan, A Rousseau… - Kidney …, 2018 - kidney-international.org
First, we agree that any catheter-related infection (CRI) rate offers room for improvement
through a bundle of hygienic measures. This should be a process in continuous …

Immunology of membranous nephropathy: from animal models to humans

RA Sinico, N Mezzina, B Trezzi… - Clinical & …, 2016 - academic.oup.com
Membranous nephropathy (MN), the leading cause of nephrotic syndrome in adults, is
characterized by the deposition of subepithelial immune deposits that consist mainly of …

Autoantibodies in the diagnosis, monitoring, and treatment of membranous nephropathy

V Tesar, Z Hruskova - Frontiers in Immunology, 2021 - frontiersin.org
The discovery of anti-podocyte antibodies in primary membranous nephropathy (MN) has
revolutionized our approach toward the diagnosis and treatment of this disease. Evaluation …

A proposal for a serology-based approach to membranous nephropathy

AS De Vriese, RJ Glassock, KA Nath… - Journal of the …, 2017 - journals.lww.com
Primary membranous nephropathy (MN) is an autoimmune disease mainly caused by
autoantibodies against the recently discovered podocyte antigens: the M-type …

Immunological pathogenesis of membranous nephropathy: focus on PLA2R1 and its role

W Liu, C Gao, H Dai, Y Zheng, Z Dong, Y Gao… - Frontiers in …, 2019 - frontiersin.org
Membranous nephropathy (MN) is the major cause of nephrotic syndrome with special
pathological features, caused by the formation of immune complexes in the space between …

Serum anti-PLA2R antibodies can be initially absent in idiopathic membranous nephropathy: seroconversion after prolonged follow-up

AE van de Logt, JM Hofstra… - Kidney …, 2015 - kidney-international.org
We report a 47-year-old patient who was diagnosed with iMN in 2005. In retrospect, the
kidney biopsy stained positive for PLA2R. Immunosuppressive treatment resulted in …