Pangenome profiling of novel drug target against vancomycin-resistant Enterococcus faecium

K Khan, K Jalal, R Uddin - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
Enterococcus faecium is a frequent causative agent of nosocomial infection mainly acquired
from outgoing hospital patients (Hospital Acquired Infection—HAIs). They are largely …

In Silico identification of potential drug targets by subtractive genome analysis of Enterococcus faecium DO

M Karim, MDN Islam, GMN Azad Jewel - BioRxiv, 2020 - biorxiv.org
Once believed to be a commensal bacteria, Enterococcus faecium has recently emerged as
an important nosocomial pathogen worldwide. A recent outbreak of E. faecium unrevealed …

Genome-Wide Identification of Potential Drug Target in Enterobacteriaceae Family: A Homology-Based Method

M Hadizadeh, SN Tabatabaiepour… - Microbial Drug …, 2018 - liebertpub.com
The Enterobacteriaceae is a large family of Gram-negative, facultative anaerobic, non-spore
forming rod-shaped bacteria that includes harmless and pathogenic organisms. The …

Identification of New Drug Target in Staphylococcus lugdunensis by Subtractive Genomics Analysis and Their Inhibitors through Molecular Docking and Molecular …

Y Alhamhoom, U Hani, FE Bennani, N Rahman… - Bioengineering, 2022 - mdpi.com
Staphylococcus lugdunensis is a coagulase-negative, Gram-positive, and human
pathogenic bacteria. S. lugdunensis is the causative agent of diseases, such as native and …

Molecular docking and simulation studies against nucleoside diphosphate kinase (NDK) of Pseudomonas aeruginosa with secondary metabolite identified by genome mining …

ZK Bagewadi, UK Aakanksha… - Journal of …, 2023 - Taylor & Francis
Pseudomonas aeruginosa is one of the leading opportunistic pathogens that causes
nosocomial pneumonia and mostly in people with cystic fibrosis. In the present study, an in …

New drug target identification in Vibrio vulnificus by subtractive genome analysis and their inhibitors through molecular docking and molecular dynamics simulations

BS Alotaibi, A Ajmal, MA Hakami, A Mahmood… - Heliyon, 2023 - cell.com
Vibrio vulnificus is a rod shape, Gram-negative bacterium that causes sepsis (with a greater
than 50% mortality rate), necrotizing fasciitis, gastroenteritis, skin, and soft tissue infection …

Proteogenomic analysis of Serratia marcescens using computational subtractive genomics approach

SE D'Souza, K Khan, R Uddin - Plos one, 2023 - journals.plos.org
Serratia marcescens, a Gram-negative bacterium (Enterobacteriaceae) is a hospital-
acquired opportunistic pathogen that infects the urinary and central nervous systems. The …

Integrated Pangenome Analysis and Pharmacophore Modeling Revealed Potential Novel Inhibitors against Enterobacter xiangfangensis

MS Almuhayawi, SK Al Jaouni, S Selim… - International Journal of …, 2022 - mdpi.com
Enterobacter xiangfangensis is a novel, multidrug-resistant pathogen belonging to the
Enterobacter genus and has the ability to acquire resistance to multiple antibiotic classes …

Capturing antibacterial natural products with in silico techniques

M Masalha, M Rayan, A Adawi… - Molecular …, 2018 - spandidos-publications.com
The aim of the present study was to index natural products in order to facilitate the discovery
of less expensive antibacterial therapeutic drugs. Thus, for modeling purposes, the present …

[HTML][HTML] Mining the proteome of Fusobacterium nucleatum subsp. nucleatum ATCC 25586 for potential therapeutics discovery: an in silico approach

AM Habib, MS Islam, M Sohel… - Genomics & …, 2016 - ncbi.nlm.nih.gov
The plethora of genome sequence information of bacteria in recent times has ushered in
many novel strategies for antibacterial drug discovery and facilitated medical science to take …