The goal of the 1000 Genomes Consortium is to characterize human genome structural
variation (SV), including forms of copy number variations such as deletions, duplications …

Alu retrotransposons are the most numerous and active mobile elements in humans,
causing genetic disease and creating genomic diversity. Mobile element scanning (ME …

Human genomes are now being rapidly sequenced, but not all forms of genetic variation are
routinely characterized. In this study, we focus on Alu retrotransposition events and seek to …

We have utilized computational biology to screen GenBank for the presence of recently
integrated Ya5 and Yb8 Alu family members. Our analysis identified 2640 Ya5 Alu family …

Alu insertions have contributed to> 11% of the human genome and∼ 30–35 Alu subfamilies
remain actively mobile, yet the characterization of polymorphic Alu insertions from short-read …

Alu elements comprise> 10% of the human genome. We have used a computational biology
approach to analyze the human genomic DNA sequence databases to determine the impact …

Alu elements represent the largest family of human mobile elements in copy number. A
controversial issue with implications for both Alu biology and human genome evolution is …

Alu elements are a family of short interspersed repeats that have mobilized throughout
primate genomes by retrotransposition over the past 65 Myr of primate evolution (for a …

Mobile elements such as Alu repeats have substantially altered the architecture of the
human genome, and de novo mobile element insertions sometimes cause genetic …

Background De novo retrotransposition of Alu elements has been recognized as a major
driver for insertion polymorphisms in human populations. In this study, we exploited Alu …