Quantitative chimerism: an independent acute leukemia prognosis indicator following allogeneic hematopoietic SCT

XY Qin, GX Li, YZ Qin, Y Wang, FR Wang… - Bone Marrow …, 2014 - nature.com
This study evaluates the prognostic significance of quantitative chimerism to monitor minimal
residual disease and predict relapse in acute leukemia (AL) patients following allogeneic …

Chimerism status is a useful predictor of relapse after allogeneic stem cell transplantation for acute leukemia

M Barrios, A Jiménez-Velasco, J Román-Gómez… - …, 2003 - haematologica.org
BACKGROUND AND OBJECTIVES: The role of hematopoietic chimerism after allogeneic
stem cell transplantation (SCT) for acute leukemia remains controversial. We studied the …

[HTML][HTML] Chimerism analysis within 6 months of allogeneic stem cell transplantation predicts relapse in acute myeloid leukemia

C Huisman, RA De Weger, L De Vries… - Bone marrow …, 2007 - nature.com
The role of chimerism analysis as a prognostic indicator of relapse after hematopoietic stem
cell transplantation (SCT) is controversial. We monitored chimerism status by short tandem …

Reliable quantification of hematopoietic chimerism after allogeneic transplantation for acute leukemia using amplification by real-time PCR of null alleles and insertion …

A Jimenez-Velasco, M Barrios, J Roman-Gomez… - Leukemia, 2005 - nature.com
Increasing mixed chimerism (MC) after allogeneic stem cell transplantation (SCT) has been
associated with a high risk of relapse in acute leukemia. We evaluated a new method for …

[HTML][HTML] Chimerism studies with quantitative real-time PCR in stem cell recipients with acute myeloid leukemia

B Wiedemann, E Klyuchnikov, N Kröger… - Experimental …, 2010 - Elsevier
OBJECTIVE: Chimerism is well-established for surveillance of acute myeloid leukemia
(AML) patients after allogeneic hematopoietic stem cell transplantation (HSCT), but …

Quantitative chimerism kinetics in relapsed leukemia patients after allogeneic hematopoietic stem cell transplantation

X Qin, GX Li, Y Qin, W Yu, FR Wang, DH Liu… - Chinese Medical …, 2012 - journals.lww.com
Background Chimerism analysis is an important tool for the surveillance of post-transplant
engraftment. It offers the possibility of identifying impending graft rejection and recurrence of …

Chimerism analysis in peripheral blood using indel quantitative real-time PCR is a useful tool to predict post-transplant relapse in acute leukemia

N Jacque, S Nguyen, JL Golmard, M Uzunov… - Bone marrow …, 2015 - nature.com
Detection of increasing mixed chimerism (IMC) using standard PCR correlates with relapse
after allo-SCT for acute leukemias (ALs). Quantitative real-time PCR of insertion/deletion …

Serial and quantitative analysis of mixed hematopoietic chimerism by PCR in patients with acute leukemias allows the prediction of relapse after allogeneic BMT

P Bader, J Beck, A Frey, PG Schlegel… - Bone marrow …, 1998 - nature.com
Within a prospective study we analyzed hematopoietic chimerism in serial peripheral blood
samples taken from 55 patients with acute leukemias (ALL 21, AML 20, MDS 14) with a …

Prognostic value of hematopoietic chimerism in patients with acute leukemia after allogeneic bone marrow transplantation: a prospective study

SJ Choi, KH Lee, JH Lee, S Kim, HJ Chung… - Bone marrow …, 2000 - nature.com
Hematopoietic chimerism as a predictive marker for the relapse of acute leukemia after
allogeneic BMT was evaluated in a prospective study. Monthly assays of hematopoietic …

Very early lineage-specific chimerism after reduced intensity stem cell transplantation is highly predictive of clinical outcome for patients with myeloid disease

FAM Kinsella, CF Inman, A Gudger, YT Chan… - Leukemia research, 2019 - Elsevier
Background The importance of chimerism status in the very early period after hematopoietic
stem cell transplantation is unclear. We determined PBMC and T-cell donor chimerism 50 …