Early mixed T‐cell chimerism is predictive of pediatric AML or MDS relapse after hematopoietic stem cell transplant

L Broglie, I Helenowski, LJ Jennings… - Pediatric Blood & …, 2017 - Wiley Online Library
Patients with acute myeloid leukemia (AML) who relapse after hematopoietic stem cell
transplantation (HCT) have dismal outcomes. Our ability to predict those at risk for relapse is …

Analysis of chimerism within specific leukocyte subsets for detection of residual or recurrent leukemia in pediatric patients after allogeneic stem cell transplantation

T Lion, H Daxberger, J Dubovsky, P Filipcik, G Fritsch… - Leukemia, 2001 - nature.com
In patients receiving allogeneic stem cell transplantation (SCT) for treatment of malignant
hematologic disorders, residual leukemia can be assessed by different methodologic …

Debate round-table: comments concerning chimerism studies

M Gonzalez, R Lopez-Perez, R Garcia-Sanz… - Leukemia, 2001 - nature.com
Allogeneic stem cell transplantation (allo-SCT) is the treatment of choice for many patients
with hematological malignancies, as well as some non-malignant hematological disorders …

SNP-based next-generation sequencing reveals low-level mixed chimerism after allogeneic hematopoietic stem cell transplantation

J Kim, IS Hwang, S Shin, JR Choi, ST Lee - Annals of Hematology, 2018 - Springer
Dear Editor, Allogeneic hematopoietic stem cell transplantation (HSCT) is an important
treatment modality for various malignant and non-malignant hematological disorders …

Earlier relapse detection after allogeneic haematopoietic stem cell transplantation by chimerism assays: digital PCR versus quantitative real-time PCR of insertion …

J Valero-Garcia, MDC González-Espinosa, M Barrios… - PLoS …, 2019 - journals.plos.org
Background The analysis of molecular haematopoietic chimerisms (HC) has become a well-
established method to monitor the transplant evolution and to assess the risk of relapse after …

[HTML][HTML] Predictive factors and impact of full donor T-cell chimerism after reduced intensity conditioning allogeneic stem cell transplantation

M Mohty, O Avinens, C Faucher, P Viens… - …, 2007 - haematologica.org
This study investigated the kinetics of CD3+-T cell chimerism (TCC) in 102 patients receiving
reduced intensity conditioning allogeneic stem cell transplantation (RIC-allo-SCT) from an …

Quantitative assessment of hematopoietic chimerism by quantitative real-time polymerase chain reaction of sequence polymorphism systems after hematopoietic stem …

X Qin, G Li, Y Qin, W Yu, F Wang, D Liu… - Chinese Medical …, 2011 - journals.lww.com
Background Analysis of changes in recipient and donor hematopoietic cell origin is
extremely useful to monitor the effect of hematopoietic stem cell transplantation (HSCT) and …

Relevance of Chimerism analysis after allogeneic stem cell transplantation

I Clemente, A Goncalo, C Faria, M Dias… - Transplantation …, 2017 - Elsevier
Hematopoietic stem cell transplantation is a potentially curative therapy for a range of
malignant and non-malignant hematological diseases. Analysis of chimerism following …

Chimerism testing after allogeneic stem cell transplantation: importance of timing and optimal technique for testing in different clinical–biological situations

T Lion - Leukemia, 2001 - nature.com
The monitoring of chimerism has become a routine diagnostic instrument at centers
performing allogeneic stem cell or bone marrow transplantation. Despite the widespread …

[HTML][HTML] Evaluation of chimerism dynamics after allogeneic hematopoietic stem cell transplantation in children with nonmalignant diseases

M Faraci, F Bagnasco, M Leoni, S Giardino… - Biology of Blood and …, 2018 - Elsevier
It is recognized that chimerism following hematopoietic stem cell transplantation (HSCT) is a
dynamic process. The aims of this study were to describe the evolution of chimerism in …