Turmeric is traditionally used as a spice and coloring in foods. Curcumin is the primary
active ingredient in the turmeric, and compelling evidence has shown that it has the ability to …

Scope The NLRP3 inflammasome responds to various pathogen‐derived factors and
danger‐associated molecules, mediating IL‐1β maturation, therefore is involved in multiple …

Aims: In the NOD-like receptor (NLR) family, the pyrin domain containing 3 (NLRP3)
inflammasome is closely related to the progression of atherosclerosis. This study aimed to …

Despite rapid progress in the understanding of systemic lupus erythematosus (SLE), there is
still an urgent need for novel and more effective interventions. Curcumin, a natural …

Curcumin is the major bioactive polyphenolic ingredient of turmeric. Increasing evidence
indicates that the health benefits of curcumin are mediated through its anti-inflammatory and …

Curcumin has shown protective potential on osteoarthritis. However, its effect on treatment of
osteoarthritis remains elusive so far. This study aimed to determine whether curcumin could …

Abstract Interleukin-1β (IL-1β) is a highly inflammatory cytokine that significantly contributes
to both acute and chronic inflammatory diseases. The secretion of IL-1β requires a unique …

NLRP3 (Nod-like receptor family pyrin domain containing 3) inflammasome has been
reported to contribute to obesity-induced inflammation and insulin resistance. However …

Background NLRP3 inflammasome mediates IL-1β maturation, therefore plays a vital role in
the development of IBD. Curcumin is known for possessing strong anti-inflammatory …

Macrophages play a critical role in the pathogenesis of metabolic diseases including gout
and type 2 diabetes. The Nod‐like receptor (NLR) family, pyrin domain containing 3 …