[HTML][HTML] Extracellular vesicle heterogeneity: subpopulations, isolation techniques, and diverse functions in cancer progression

E Willms, C Cabañas, I Mäger, MJA Wood… - Frontiers in …, 2018 - frontiersin.org
Cells release membrane enclosed nano-sized vesicles termed extracellular vesicles (EVs)
that function as mediators of intercellular communication by transferring biological …

[HTML][HTML] Focus on extracellular vesicles: new frontiers of cell-to-cell communication in cancer

C Ciardiello, L Cavallini, C Spinelli, J Yang… - International journal of …, 2016 - mdpi.com
Extracellular Vesicles (EVs) have received considerable attention in recent years, both as
mediators of intercellular communication pathways that lead to tumor progression, and as …

[HTML][HTML] Extracellular vesicles in the tumor microenvironment: old stories, but new tales

L Han, EWF Lam, Y Sun - Molecular cancer, 2019 - Springer
Mammalian cells synthesize and release heterogeneous extracellular vesicles (EVs) which
can be generally recognized as subclasses including exosomes, microvesicles (MVs), and …

Extracellular vesicles as emerging targets in cancer: Recent development from bench to bedside

K Wu, F Xing, SY Wu, K Watabe - … et Biophysica Acta (BBA)-Reviews on …, 2017 - Elsevier
Extracellular vesicles (EVs) have emerged as important players of cancer initiation and
progression through cell-cell communication. They have been recognized as critical …

[HTML][HTML] Tumor-derived extracellular vesicles: multifunctional entities in the tumor microenvironment

JW Clancy, C D'Souza-Schorey - Annual Review of Pathology …, 2023 - annualreviews.org
Tumor cells release extracellular vesicles (EVs) that can function as mediators of
intercellular communication in the tumor microenvironment. EVs contain a host of bioactive …

[HTML][HTML] A comprehensive picture of extracellular vesicles and their contents. Molecular transfer to cancer cells

A Jurj, O Zanoaga, C Braicu, V Lazar, C Tomuleasa… - Cancers, 2020 - mdpi.com
Critical processes such as growth, invasion, and metastasis of cancer cells are sustained via
bidirectional cell-to-cell communication in tissue complex environments. Such …

[HTML][HTML] Extracellular vesicles–biomarkers and effectors of the cellular interactome in cancer

J Rak - Frontiers in pharmacology, 2013 - frontiersin.org
In multicellular organisms both health and disease are defined by patterns of communication
between the constituent cells. In addition to networks of soluble mediators, cells are also …

[HTML][HTML] Extracellular vesicles: emerging targets for cancer therapy

P Vader, XO Breakefield, MJA Wood - Trends in molecular medicine, 2014 - cell.com
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are
released by almost all cell types, including tumour cells. Through transfer of their molecular …

Extracellular vesicles in cancer diagnostics and therapeutics

A Shehzad, SU Islam, R Shahzad, S Khan… - Pharmacology & …, 2021 - Elsevier
Cancer promotion, development, and malignant transformation is greatly influenced by cell-
to-cell interactions in a complex tissue microenvironment. Cancer and stromal cells secrete …

Extracellular vesicles in cancer—implications for future improvements in cancer care

R Xu, A Rai, M Chen, W Suwakulsiri… - Nature reviews Clinical …, 2018 - nature.com
The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional
cell–cell communication within complex tissue environments. Such communication …