The mechanism by which gap junction proteins, connexins, act as potent tumor suppressors
remains poorly understood. In this study human breast tumor cells were found to exhibit …

Connexins are gap junction proteins that assemble into channels that mediate direct
intercellular communication. Connexins are well-documented tumor suppressors and are …

A growing body of evidence indicates that the gap junction (GJ) plays a pivotal role in tumor
suppression by exerting cell‐cell communication. It has, however, been reported that …

We previously reported that over-expression of connexins in mammary tumor cells retarded
tumor growth in vivo in the absence of appreciable gap junction formation, highlighting a …

Connexins are tumor suppressors, and human breast connexin 26 (Cx26) and connexin 43
(Cx43) gap junctions are often down-regulated in breast cancer. We previously showed that …

There is a large body of evidence suggesting the connexin gap junction proteins appear to
act as tumor suppressors, and their tumor inhibitory effect is usually attributed to their main …

It has been well established that the restoration of connexin expression in tumor cells often
leads to a partial reversion of tumor cell phenotypes and increased growth control. In this …

Gap junctions are intercellular channels that are formed from members of a family of
proteins, the connexins (Cxs). Gap junctions play an important role in vital functions …

Gap junctions, the channels formed by the connexin (Cx) family of proteins, are responsible
for direct intercellular communication. Although connexins are considered as tumor …

Our laboratory has previously reported that transfection of a connexin26 (Cx26) gene, but
not connexin40 nor connexin43 (Cx43), into HeLa cells expressing no detectable level of …