Mechanisms of Trypanosoma cruzi persistence in Chagas disease

F Nagajyothi, FS Machado, BA Burleigh… - Cellular …, 2012 - Wiley Online Library
Trypanosoma cruzi infection leads to development of chronic Chagas disease. In this article,
we provide an update on the current knowledge of the mechanisms employed by the …

Trypanosoma cruzi: Parasite and Host Cell Signaling during the Invasion Process

N Yoshida, M Cortez - Molecular Mechanisms of Parasite Invasion …, 2008 - Springer
Mammalian cell invasion by Trypanosoma cruzi is a complex process in which various
parasite and host cell components interact, triggering the activation of signaling cascades …

Host cell invasion by Trypanosoma cruzi: a unique strategy that promotes persistence

MC Fernandes, NW Andrews - FEMS microbiology reviews, 2012 - academic.oup.com
The intracellular protozoan parasite Trypanosoma cruzi is the causative agent of Chagas'
disease, a serious disorder that affects millions of people in Latin America. Despite the …

Molecular mechanisms of host cell invasion by Trypanosoma cruzi

CL Epting, BM Coates, DM Engman - Experimental parasitology, 2010 - Elsevier
The protozoan parasite Trypanosoma cruzi, the etiologic agent of Chagas disease, is an
obligate intracellular protozoan pathogen. Overlapping mechanisms ensure successful …

Evasion of the Immune Response by Trypanosoma cruzi during Acute Infection

MS Cardoso, JL Reis-Cunha… - Frontiers in …, 2016 - frontiersin.org
Trypanosoma cruzi is the etiologic agent of Chagas disease, a neglected tropical disease
that affects millions of people mainly in Latin America. To establish a life-long infection, T …

Review on Trypanosoma cruzi: Host Cell Interaction

W De Souza, TMU De Carvalho… - International journal of …, 2010 - Wiley Online Library
Trypanosoma cruzi, the causative agent of Chagas′ disease, which affects a large number
of individuals in Central and South America, is transmitted to vertebrate hosts by blood …

Trypanosoma cruzi Infection and Host Lipid Metabolism

Q Miao, M Ndao - Mediators of Inflammation, 2014 - Wiley Online Library
Trypanosoma cruzi is the causative agent of Chagas disease. Approximately 8 million
people are thought to be affected worldwide. Several players in host lipid metabolism have …

Cell signalling and Trypanosoma cruzi invasion

BA Burleigh, AM Woolsey - Cellular microbiology, 2002 - Wiley Online Library
Mammalian cell invasion by the protozoan pathogen Trypanosoma cruzi is critical to its
survival in the host. To promote its entry into a wide variety of non‐professional phagocytic …

The Trypanosoma cruzi–host-cell interplay: location, invasion, retention

LO Andrade, NW Andrews - Nature Reviews Microbiology, 2005 - nature.com
Chagas disease is a debilitating human illness caused by infection with the protozoan
Trypanosoma cruzi. A capacity to invade and replicate within many different cell types is a …

The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease

C Junqueira, B Caetano, DC Bartholomeu… - Expert reviews in …, 2010 - cambridge.org
Infection with the protozoan parasite Trypanosoma cruzi, the agent of Chagas disease, is
characterised by a variable clinical course–from symptomless cases to severe chronic …