Tuberculosis (TB) is a leading cause of death worldwide following infection with
Mycobacterium tuberculosis (Mtb), with 1.5 million deaths from this disease reported in …

It has long been recognized that tuberculosis (TB) induces both protective and tissue
damaging immune responses. This paper reviews nearly two centuries of evidence that …

Progress toward developing new strategies to control the spread of Mycobacterium
tuberculosis is limited by a poor understanding of the basic pathogenesis of post‐primary …

Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …

Mycobacterium tuberculosis is an extremely successful pathogen that demonstrates the
capacity to modulate its host both at the cellular and tissue levels. At the cellular level, the …

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains a
leading cause of death due to infection in humans. To more effectively combat this …

Immunology is a central theme when it comes to tuberculosis (TB). The outcome of human
infection with Mycobacterium tuberculosis is dependent on the ability of the immune …

The granuloma that forms in response to Mycobacterium tuberculosis must be carefully
balanced in terms of immune responses to provide sufficient immune cell activation to inhibit …

Introduction: Inflammation, or the prolonged resolution of inflammation, contributes to death
from tuberculosis. Interest in inflammatory mechanisms and the prospect of beneficial …

Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for
millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host …