Dietary selenium excess affected spermatogenesis via DNA damage and telomere-related cell senescence and apoptosis in mice
Y Zhang, J Liu, X Li, G Zhou, Y Sang, M Zhang… - Food and Chemical …, 2023 - Elsevier
Selenium (Se) is a vital microelement for spermatogenesis and male fertility. The aim of this
study was to investigate the effects of Se on the male reproductive function and possible …
study was to investigate the effects of Se on the male reproductive function and possible …
Both selenium deficiency and excess impair male reproductive system via inducing oxidative stress-activated PI3K/AKT-mediated apoptosis and cell proliferation …
Z Xu, M Liu, QJ Niu, YX Huang, L Zhao, XG Lei… - Free Radical Biology …, 2023 - Elsevier
Selenium (Se) deficiency or excess impairs testicular development and spermatogenesis,
while the underlying mechanisms in this regard remain unclear. This study was designed to …
while the underlying mechanisms in this regard remain unclear. This study was designed to …
Selenium variation induced oxidative stress regulates p53 dependent germ cell apoptosis: plausible involvement of HSP70-2
N Kaushal, MP Bansal - European journal of nutrition, 2009 - Springer
Background Selenium at altered concentration causes abnormal spermatogenesis and male
infertility. However, the exact mechanism behind this is still unexplored. Aims It was aimed to …
infertility. However, the exact mechanism behind this is still unexplored. Aims It was aimed to …
Dietary selenium variation-induced oxidative stress modulates CDC2/cyclin B1 expression and apoptosis of germ cells in mice testis
N Kaushal, MP Bansal - The Journal of nutritional biochemistry, 2007 - Elsevier
Oxidative stress has been linked with apoptosis in germ cells and with male infertility.
However, the molecular mechanism of oxidative-stress-mediated apoptosis in germ cells …
However, the molecular mechanism of oxidative-stress-mediated apoptosis in germ cells …
Low-Se diet can affect sperm quality and testicular glutathione peroxidase-4 activity in rats
Q Wang, S Zhan, Y Liu, F Han, L Shi, C Han… - … Trace Element Research, 2021 - Springer
This study aimed to observe the influence of selenium (Se) deficiency on sperm quality and
selenoprotein expression in rats. Four-week male Wista rats were randomly divided into …
selenoprotein expression in rats. Four-week male Wista rats were randomly divided into …
Apoptosis induced by modulation in selenium status involves p38 MAPK and ROS: implications in spermatogenesis
P Ranawat, MP Bansal - Molecular and cellular biochemistry, 2009 - Springer
Selenium has been linked to cell survival and apoptosis. Apoptosis plays an important role
in spermatogenesis. Evidence suggests that reactive oxygen species induce apoptotic …
in spermatogenesis. Evidence suggests that reactive oxygen species induce apoptotic …
Effect of selenium-induced oxidative stress on the cell kinetics in testis and reproductive ability of male mice
P Kaur, MP Bansal - Nutrition, 2005 - Elsevier
OBJECTIVE: The present study evaluated the role of experimental oxidative stress (induced
by feeding diets with different concentrations of selenium [Se], a trace nutrient and potent …
by feeding diets with different concentrations of selenium [Se], a trace nutrient and potent …
Antioxidant effects of selenium on sperm parameters and testicular structure in young and aged mice
S Mohammadi, M Movahedin… - Journal of reproduction …, 2008 - search.proquest.com
Introduction: Selenium, as an antioxidant, is essential for normal testicular function and
spermatogenesis. It can reduce free oxidative radicals as a cofactor for antioxidant enzymes; …
spermatogenesis. It can reduce free oxidative radicals as a cofactor for antioxidant enzymes; …
Dietary selenium supplementation ameliorates female reproductive efficiency in aging mice
H Yang, IH Qazi, B Pan, C Angel, S Guo, J Yang… - Antioxidants, 2019 - mdpi.com
Female reproductive (ovarian) aging is distinctively characterized by a markedly reduced
reproductive function due to a remarkable decline in quality and quantity of follicles and …
reproductive function due to a remarkable decline in quality and quantity of follicles and …
Optimum doses and forms of selenium maintaining reproductive health via regulating homeostasis of gut microbiota and testicular redox, inflammation, cell …
YQ Yan, M Liu, ZJ Xu, ZJ Xu, YX Huang, XM Li… - The Journal of …, 2024 - Elsevier
Background There is a U-shaped relationship between dietary selenium (Se) ingestion and
optimal sperm quality. Objectives This study aimed to investigate the optimal dietary dose …
optimal sperm quality. Objectives This study aimed to investigate the optimal dietary dose …
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