The cystic fibrosis transmembrane conductance regulator CFTR gene is found on
chromosome 7 [Kerem, B., Rommens, JM, Buchanan, JA, Markiewicz, D., Cox, TK …

Introduction: Cystic fibrosis is an autosomal recessive disorder caused by mutations in the
cystic fibrosis transmembrane conductance regulator (CFTR) gene that codes for the CFTR …

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene result in
defective epithelial cAMP-dependent Cl− secretion and increased airway Na+ absorption …

Cystic fibrosis (CF) is the most common lethal inherited disorder in Caucasians. It is caused
by mutation of the CF transmembrane conductance regulator (CFTR) gene. A defect in the …

Cystic fibrosis transmembrane conductance regulator (CFTR) is an epithelial Cl–channel
expressed in luminal membranes of secretory and reabsorptive epithelia. CFTR plays a …

The tracheobronchial submucosal glands secrete liquid that is important for hydrating airway
surfaces, supporting mucociliary transport, and serving as a fluid matrix for numerous …

The cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride channel that
is defective in cystic fibrosis, and has also been closely associated with ATP permeability in …

Abnormal airway secretions characterize asthma" and cystic fibrosis (CF), 13.73 obstructive
airway diseases with different clinical courses. Whereas airway secretions that are retained …

The cystic fibrosis transmembrane conductance regulator (CFTR) is an integral membrane
glycoprotein which functions as an anion channel and influences diverse cellular processes …

The most common mutation in the CFTR gene in individuals with cystic fibrosis (CF), ΔF508,
leads to the absence of CFTR Cl− channels in the apical plasma membrane, which in turn …