In-silico clearing approach for deep refractive index tomography by partial reconstruction and wave-backpropagation

O Yasuhiko, K Takeuchi - Light: Science & Applications, 2023 - nature.com
Refractive index (RI) is considered to be a fundamental physical and biophysical parameter
in biological imaging, as it governs light-matter interactions and light propagation while …

Deep learning-based optical field screening for robust optical diffraction tomography

DH Ryu, YJ Jo, J Yoo, T Chang, D Ahn, YS Kim… - Scientific reports, 2019 - nature.com
In tomographic reconstruction, the image quality of the reconstructed images can be
significantly degraded by defects in the measured two-dimensional (2D) raw image data …

Quantitative 3D refractive index tomography of opaque samples in epi-mode

P Ledwig, FE Robles - Optica, 2020 - opg.optica.org
Three-dimensional (3D) refractive index (RI) tomography has recently become an exciting
new tool for biological studies. However, its limitation to (1) thin samples resulting from a …

ODTbrain: a Python library for full-view, dense diffraction tomography

P Müller, M Schürmann, J Guck - BMC bioinformatics, 2015 - Springer
Background Analyzing the three-dimensional (3D) refractive index distribution of a single
cell makes it possible to describe and characterize its inner structure in a marker-free …

Unlocking the secrets of the invisible world: incredible deep optical imaging through in-silico clearing

TH Xiao, Y Zhou, K Goda - Light: Science & Applications, 2023 - nature.com
In-silico clearing enables deep optical imaging of biological samples by correcting image
blur caused by scattering and aberration. This breakthrough method offers researchers …

[HTML][HTML] Computational approach to dark-field optical diffraction tomography

T Chang, S Shin, M Lee, YK Park - Apl Photonics, 2020 - pubs.aip.org
The measurement of three-dimensional (3D) images and the analysis of subcellular
organelles are crucial for the study of the pathophysiology of cells and tissues. Optical …

Beyond Born-Rytov limit for super-resolution optical diffraction tomography

JW Lim, A Wahab, GS Park, KR Lee, YK Park… - Optics express, 2017 - opg.optica.org
Optical diffraction tomography (ODT) using Born or Rytov approximation suffers from severe
distortions in reconstructed refractive index (RI) tomograms when multiple scattering occurs …

Refractive index tomography with structured illumination

S Chowdhury, WJ Eldridge, A Wax, J Izatt - Optica, 2017 - opg.optica.org
To probe biological questions with significant biophysical, biochemical, and molecular
components, an imaging solution compatible with both endogenous and molecular 3D …

Optical tissue clearing associated with 3D imaging: application in preclinical and clinical studies

C Brenna, C Simioni, G Varano, I Conti… - Histochemistry and Cell …, 2022 - Springer
Understanding the inner morphology of intact tissues is one of the most competitive
challenges in modern biology. Since the beginning of the twentieth century, optical tissue …

Distortion matrix concept for deep optical imaging in scattering media

A Badon, V Barolle, K Irsch, AC Boccara, M Fink… - Science …, 2020 - science.org
In optical imaging, light propagation is affected by the inhomogeneities of the medium.
Sample-induced aberrations and multiple scattering can strongly degrade the image …