Simple Summary Spinal cord injury often disrupts connections between the brain and spinal
cord leading to a plethora of health complications, including bladder dysfunction. Spinal …

Spinal cord injury (SCI) above the lumbosacral level often leads to dysfunction of the lower
urinary tract (LUT) including detrusor hyper-reflexia, wherein bladder compliance is low …

Spinal cord injury (SCI) above the lumbosacral level results in lower urinary tract
dysfunction, including (1) detrusor hyperreflexia, wherein bladder compliance is low, and (2) …

Aims Serotonin affects micturition in the normal rat through actions not only on ascending
and descending spinal pathways and supraspinal centers but also on the lumbosacral …

After spinal cord injury, the upward conduction of the spinal cord is lost, resulting in the loss
of micturition control, which manifests as detrusor sphincter dyssynergia and insufficient …

Objectives To investigate whether the voiding dysfunction caused by spinal cord injury (SCI)
in rats can be improved by iv administration of the serotonin (5‐HT) 2A/2C receptor agonist …

5‐Hydroxytryptamine (5‐HT) receptors in the central nervous system have been implicated
in the control of micturition. In rats and cats, spinal and supraspinal reflex pathways involved …

Purpose: The serotonin 5-hydroxytryptamine1A/7 receptor agonist (R)-8-OH-DPAT (8-
hydroxy-2-(di-n-propylamino) tetralin)(Sigma®) and the 5-hydroxytryptamine1A/1B/1D …

Coordination of the bladder detrusor and the external urethral sphincter is a supraspinally
controlled reflex that is essential for efficient micturition. This coordination is permanently lost …

Aims To better understand the effects of the selective 5‐HT7 receptor agonist 4‐[2‐
(Methylthio) phenyl]‐N‐(1, 2, 3, 4‐tetrahydro‐1‐naphthalenyl)‐1‐piperazinehexanamide …