Emerging research demonstrates that diet, pollution, and other environmental triggers can
alter both the function and expression of human genes and lead to a heightened disease …

The brave new world envisioned by proponents of personalized medicine has attracted
considerable interest and investment during the past decade or so. The excitement is …

Objective Health or disease is shaped for all individuals by interactions between their genes
and environment. Exactly how the environment changes gene expression and how this can …

The effects of environmental factors and epigenetics on health and disease development
are complex and interconnected. Environmental factors encompass external influences like …

Concerns have been raised about the value of genomic research for prevention and public
health, especially for complex diseases with risk factors that are amenable to environmental …

Public interest in human genome research hinges on its promise for improving human
health, perhaps the ultimate ambition of the Human Genome Project. 1 Sequencing the …

Human illness is caused by many interrelated factors including aging, inherited genetic
predispositions, and a variety of environmental exposures. There is increasing awareness of …

Recent advances in human and molecular genetics provide an unparalleled opportunity to
understand how genes and genetic changes interact with environmental stimuli to either …

Background Pathogenesis of complex diseases involves the integration of genetic and
environmental factors over time, making it particularly difficult to tease apart relationships …

In recent years, research on how the human environment and lifestyle influence gene
expression has generated considerable scientific and public interest. Articles in prominent …