Dynamic preservation of organ grafts by hypothermic machine perfusion (HMP) has
regained broader interest to provide better outcome after transplantation. One pivotal aspect …

Background Hypothermic machine perfusion (HMP) for preservation led to compelling
success for outcomes of renal transplantation. Application of different concentrations of …

Background Supplemental oxygenation of the standard hypothermic machine perfusion
(HMP) circuit has the potential to invoke favorable changes in metabolism, optimizing …

Background. The aim of this feasibility study was to determine an alternative oxygenation
technique (easy, cheap, and compatible with air transport) for membrane oxygenation …

With oxygenation proposed as a resuscitative measure during hypothermic models of
preservation, the aim of this study was to evaluate the optimal start time of oxygenation …

Background. Hypothermic machine perfusion (HMP) has become standard care in many
center's to preserve kidneys donated after circulatory death (DCD). Despite a significant …

Organ preservation has historically relied on the concept that by reducing the temperature to
4 C, cellular metabolism is reduced to approximately 10% of normal. 1 Therefore, it is …

Objective: To study graft function and ischemia/reperfusion injury of porcine kidneys after
preservation with the new Groningen Machine Perfusion (GMP) system versus static cold …

Most kidney grafts are marginal and from deceased donors, which yield worse clinical
outcomes. Hypothermic machine perfusion has created a paradigm shift in kidney …

Background Deceased after cardiac death donors (DCDs) represent a valuable source of
organs; however, preventing poor outcome is difficult, even with the use of machine …