[图书][B] Animals and alternatives in toxicology: present status and future prospects

M Balls, J Bridges, J Southee - 1991 - Springer
This volume considers the second report of the FRAME Toxicity Committee presenting
reviews and discussions by invited authors and general discussions. It covers developments …

Progress in Toxicological Testing: Reduction and Refinement Issues: Recommendations from a Joint UK Government/ECVAM Meeting

K Tichias, J Fentem, D Basketter… - Alternatives to …, 1998 - journals.sagepub.com
This is the report of a meeting organised jointly by the UK Government and the European
Centre for the Validation of Alternative Methods (ECV AM), a unit of the European …

Workshop overview: scientific and regulatory challenges for the reduction, refinement, and replacement of animals in toxicity testing

IFH Purchase, PA Botham, LH Bruner, OP Flint… - Toxicological …, 1998 - Elsevier
Public concern for animal welfare has been expressed through legislative control of animal
use for experimental purposes since the first legislation was introduced in 1876 in the United …

Alternatives to and reduction of animal use in biomedical research, education and testing

JM Frazier, AM Goldberg - Alternatives to Laboratory …, 1990 - journals.sagepub.com
Biomedical endeavours can be divided into three major categories: research, education,
and testing. Within the context of each of these categories, activities involving whole animals …

An assessment of progress in the use of alternatives in toxicity testing since the publication of the report of the Second FRAME Toxicity Committee (1991)

R Combes, M Balls, L Bansil, M Barratt… - Alternatives to …, 2002 - journals.sagepub.com
The first FRAME Toxicity Committee was formed in October 1979, with the following remit: a)
to conduct a thorough review of current toxicity testing procedures, to assess their reliability …

Comments on the scientific validation and regulatory acceptance of in vitro toxicity tests

M Balls, RH Clothier - Toxicology in vitro, 1991 - Elsevier
The 1980s saw widespread acceptance of the Three Rs (reduction, refinement,
replacement) concept of alternatives, and a great deal of effort was put into the development …

Types of toxicity and applications of toxicity testing

AP Worth - The history of alternative test methods in toxicology, 2019 - Elsevier
This chapter explains why toxicity testing is carried out for the purposes of protecting human
health or the environment. The traditional reliance on animal testing and the challenges …

The use of animals in testing

R Heywood - Alternatives to Laboratory Animals, 1987 - journals.sagepub.com
When planes crash, rockets explode or ferries capsize, people reflect on the price of
technology's benefits. The demand is to make things safer, fixing the design, improving the …

The Fund for the Replacement of Animals in Medical Experiments (FRAME): 23 years of campaigning for the Three Rs

M Balls, JH Fentem - Alternatives to Animal Testing: New Ways …, 1994 - Wiley Online Library
Summary The Fund for the Replacement of Animals in Medical Experiments (FRAME) was
established in 1969, to work to relieve the suffering of animals used as subjects in …

The Third FRAME Toxicity Committee: working toward greater implementation of alternatives in toxicity testing

RD Combes, M Balls, L Bansil… - Alternatives to …, 2004 - journals.sagepub.com
FRAME (the Fund for the Replacement of Animals in Medical Experiments; http://www.
frame. org. uk) is a scientific charity, which has, for over 30 years, been advocating and …