BACKGROUND: Increasing incidence of pertussis in adolescents and adults has stimulated
the development of safe and immunogenic acellular pertussis vaccines for booster …

The aim of this assessor-blinded trial was to compare the immunogenicity and reactogenicity
of a candidate diphtheria, tetanus toxoids and acellular pertussis vaccine with reduced …

Background Increasing evidence shows that protection induced by acellular pertussis
vaccines is short-lived, requiring repeated booster vaccination to control pertussis disease …

Pertussis causes substantial morbidity among adolescents and adults, as well as other
persons in contact with affected individuals. In the context of widespread childhood …

We compared immunogenicity and reactogenicity of a single dose of DTaP vaccine
(containing tetanus and diphtheria toxoids and four acellular pertussis antigens) with …

Background: Due to the resurgence of pertussis, many countries have revised the pertussis
immunization schedules and recommended booster doses of pertussis component vaccine …

This review offers a perspective on the acellular pertussis vaccine efficiency trials concluded
in the 1990s and presents the main conclusions of a meta-analysis of 52 studies that …

A single blinded randomized controlled trial to compare the reactogenicity and
immunogenicity of adult formulated dTpa and monovalent pa vaccines with a licensed Td …

Objective: To assess the efficacy and safety of whole-cell and acellular pertussis vaccines
administered to children singly or within diphtheria, tetanus and pertussis (DTP) vaccines …

ABSTRACT Background: An acellular Pertussis (aP) vaccine containing recombinant
genetically detoxified Pertussis Toxin (PTgen), Filamentous Hemagglutinin (FHA) and …