Diverse biological activities of 1, 3, 4-thiadiazole scaffold

T Anthwal, S Paliwal, S Nain - Chemistry, 2022 - mdpi.com
The chemistry of 1, 3, 4-thiadiazole is one of the most interesting scaffolds for synthesizing
new drug molecules due to their numerous pharmacological activities. Several modifications …

1, 3, 4-thiadiazole: A privileged scaffold for drug design and development

X Han, YL Yu, YS Hu, XH Liu - Current Topics in Medicinal …, 2021 - ingentaconnect.com
1, 3, 4-thiadiazole is a five-membered aromatic heterocycle containing two nitrogen atoms
and one sulfur atom. As a privileged scaffold, it has its unique chemical properties and …

Synthetic transformations and medicinal significance of 1, 2, 3-thiadiazoles derivatives: An update

A Irfan, S Ullah, A Anum, N Jabeen, AF Zahoor… - Applied Sciences, 2021 - mdpi.com
The 1, 2, 3-thiadiazole moiety occupies a significant and prominent position among
privileged heterocyclic templates in the field of medicine, pharmacology and pharmaceutics …

An overview on synthetic 2-aminothiazole-based compounds associated with four biological activities

M Farouk Elsadek, B Mohamed Ahmed… - Molecules, 2021 - mdpi.com
Amongst sulfur-and nitrogen-containing heterocyclic compounds, the 2-aminothiazole
scaffold is one of the characteristic structures in drug development as this essential …

[PDF][PDF] Thiadiazoles: Progress report on biological activities

SKGP Kempegowda, DP Kumar, M TT - Der Pharma Chemica, 2011 - researchgate.net
ABSTRACT Chemical properties of 1, 3, 4-thiadiazole have been reviewed in last fast five
year. However, usefulness of 1, 3, 4-thiadiazole has a privileged system in the medicinal has …

A mini-review on pharmacological importance of benzothiazole scaffold

M Asif, M Imran - Mini-Reviews in Organic Chemistry, 2021 - ingentaconnect.com
Heterocyclic compounds are important because they have almost all types of
pharmacological properties. Due to these properties of heterocyclic compounds, they …

A review on recent synthetic strategies and pharmacological importance of 1, 3-thiazole derivatives

S Nayak, SL Gaonkar - Mini reviews in medicinal chemistry, 2019 - ingentaconnect.com
Thiazole is the most common heterocyclic compound in heterocyclic chemistry and in drug
design. Presence of several reaction sites in the thiazole moiety extends their range of …

[PDF][PDF] 1, 3, 4-Thiadiazole: A biologically active scaffold

H Khalilullah, MU Khan, D Mahmood… - Int. J. Pharm. Pharm …, 2014 - researchgate.net
There has been considerable interest in the development of novel compounds with
anticonvulsant, antidepressant, analgesic, anti-inflammatory, anti allergic, antipsychotic …

1, 3, 4-Thiadiazoles: A potent multi targeted pharmacological scaffold

S Haider, MS Alam, H Hamid - European journal of medicinal chemistry, 2015 - Elsevier
Despite a significant work on thiadiazoles, continuous efforts are still being made to identify
novel heterocyclic compounds with potent biological activities. This review may help the …

[PDF][PDF] Common methods to synthesize benzothiazole derivatives and their medicinal significance

SL Khokra, K Arora, H Mehta, A Aggarwal… - International Journal of …, 2011 - Citeseer
Recently, heterocyclic compounds analogues and their derivatives have attracted strong
interest in medicinal chemistry due to their biological and pharmacological properties. The …