Viruses are used as expression vectors for protein synthesis, immunology research,
vaccines, and therapeutics. Advantages of poxvirus vectors include the accommodation of …

The gene encoding bacteriophage T7 RNA polymerase (T7gene1) was placed under the
control of regulatory elements from the Escherichia coli lac operon to construct an inducible …

Recombinant DNA technology has made it possible to develop molecular cloning vectors
that allow the expression of heterologous genes in a variety of animal viruses. This chapter …

Vaccinia virus, a member of the poxvirus family, is widely used as a mammalian cell
expression vector. Vaccinia virus replicates in the cytoplasm and has its own transcriptional …

Various vaccinia virus (VACV) strains were applied during the smallpox vaccination
campaign to eradicate the variola virus worldwide. After the eradication of smallpox, VACV …

Poxviruses are widely used for the cytoplasmic expression of recombinant genes in
mammalian cells. Recent improvements allow high expression and simplify the integration …

Vaccinia virus (VACV) was successfully used as a vaccine in the smallpox eradication
campaign. Since then, it has been widely used in the development of vaccine and …

The vaccinia virus/bacteriophage T7 hybrid transient expression system employs a
recombinant vaccinia virus that encodes the T7 RNA polymerase gene, a plasmid vector …

Vaccinia virus is an efficient expression vector with broad host range infectivity and large
DNA capacity. This vector has been particularly useful for identifying target antigens for …

Vaccinia virus vectors for gene expression Page 1 Vaccinia virus vectors for gene expression
Geoffrey L. Smith Sir William Dunn School of Pathology, University of Oxford, South Parks …