Metastable and somatically heritable patterns of DNA methylation provide an important level
of genomic regulation. In this article, we review methods for analyzing these genome-wide …

Methylation of cytosine bases in DNA provides a layer of epigenetic control in many
eukaryotes that has important implications for normal biology and disease. Therefore …

DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …

DNA methylation is a biochemical process where a DNA base, usually cytosine, is
enzymatically methylated at the 5-carbon position. An epigenetic modification associated …

DNA methylation is an epigenetic mark that has suspected regulatory roles in a broad range
of biological processes and diseases. The technology is now available for studying DNA …

DNA methylation is one of the most important heritable epigenetic modifications of the
genome and is involved in the regulation of many cellular processes. Aberrant DNA …

With the rapid development of genome-wide high-throughput technologies, including
expression arrays, SNP arrays and next-generation sequencing platforms, enormous …

The number of epigenetic studies is exponentially increasing. There is anticipation that DNA
methylation may close gaps in our understanding of disease etiology, and how certain risk …

DNA methylation plays a critical role in genome function both in health and disease. Almost
60 years after the discovery of 5-methyl cytosine and∼ 25 years since the discovery that …

The haploid human genome contains approximately 29 million CpGs that exist in a
methylated, hydroxymethylated or unmethylated state, collectively referred to as the DNA …