In this study, we have developed a sophisticated microscopic imaging system that integrates
cutting-edge photoacoustic, ultrasonic, and fluorescence microscopy imaging technologies …

Intense efforts are underway to develop functional imaging modalities for capturing brain
activity at the whole organ scale with high spatial and temporal resolution. Functional …

The blood-brain barrier (BBB) can be transiently and locally opened by focused ultrasound
(FUS) in the presence of microbubbles (MBs). Various imaging modalities and contrast …

Focused ultrasound (FUS) stimulation is a promising neuromodulation technique with the
merits of non-invasiveness, high spatial resolution, and deep penetration depth. However …

Hemodynamic functional ultrasound imaging (fUS) of neural activity provides a unique
combination of spatial coverage, spatiotemporal resolution and compatibility with freely …

The conventional fluorescence imaging has limited spatial resolution in centimeter-deep
tissue because of the tissue's high scattering property. Ultrasound-switchable fluorescence …

BACKGROUND: Low intensity, transcranial focused ultrasound (tFUS) is a re-emerging
brain stimulation technique with the unique capability of reaching deep brain structures non …

Functional ultrasound (fUS) makes use of high frame-rate Power Doppler Images to
measure a proxy for neuronal activity through the mechanism of neurovascular coupling …

Red blood cell velocity (RBCv), cerebral blood flow (CBF), and volume (CBV) are three key
parameters when describing brain hemodynamics. Functional ultrasound imaging is a …

Functional ultrasound (fUS) imaging is a method for visualizing deep brain activity based on
cerebral blood volume changes coupled with neural activity, while functional MRI (fMRI) …