Focused ultrasound in the human brain: Current and emerging applications

N Lipsman - The Journal of the Acoustical Society of America, 2023 - pubs.aip.org
MR-guided Focused ultrasound (MRgFUS) is a disruptive medical technology, and its
implementation in the clinic represents the culmination of decades of research. Lying at the …

[引用][C] 聚焦超声在脑部疾病的应用进展

李进丹, 许泽艳, 王瑞, 杨军, 廖承德 - 中国医学影像技术, 2019

[HTML][HTML] Acoustic biomolecules enhance hemodynamic functional ultrasound imaging of neural activity

D Maresca, T Payen, A Lee-Gosselin, B Ling… - NeuroImage, 2020 - Elsevier
Hemodynamic functional ultrasound imaging (fUS) of neural activity provides a unique
combination of spatial coverage, spatiotemporal resolution and compatibility with freely …

[HTML][HTML] Hemodynamic response to sensory stimulation in mice: Comparison between functional ultrasound and optoacoustic imaging

J Robin, R Rau, B Lafci, A Schroeter, M Reiss… - NeuroImage, 2021 - Elsevier
Intense efforts are underway to develop functional imaging modalities for capturing brain
activity at the whole organ scale with high spatial and temporal resolution. Functional …

[HTML][HTML] Contrast-enhanced ultrasound imaging for the detection of focused ultrasound-induced blood-brain barrier opening

CH Fan, WH Lin, CY Ting, WY Chai, TC Yen, HL Liu… - Theranostics, 2014 - ncbi.nlm.nih.gov
The blood-brain barrier (BBB) can be transiently and locally opened by focused ultrasound
(FUS) in the presence of microbubbles (MBs). Various imaging modalities and contrast …

In vivo ultrasound-switchable fluorescence imaging

T Yao, S Yu, Y Liu, B Yuan - Scientific Reports, 2019 - nature.com
The conventional fluorescence imaging has limited spatial resolution in centimeter-deep
tissue because of the tissue's high scattering property. Ultrasound-switchable fluorescence …

[HTML][HTML] Chronic brain functional ultrasound imaging in freely moving rodents performing cognitive tasks

A El Hady, D Takahashi, R Sun, O Akinwale… - Journal of neuroscience …, 2024 - Elsevier
Background: Functional ultrasound imaging (fUS) is an emerging imaging technique that
indirectly measures neural activity via changes in blood volume. Chronic fUS imaging during …

[HTML][HTML] Functional ultrasound (fUS) imaging of displacement-guided focused ultrasound (FUS) neuromodulation in mice

S Kim, N Kwon, MM Hossain, J Bendig, EE Konofagou - bioRxiv, 2024 - ncbi.nlm.nih.gov
Focused ultrasound (FUS) stimulation is a promising neuromodulation technique with the
merits of non-invasiveness, high spatial resolution, and deep penetration depth. However …

[HTML][HTML] Brain-wide mapping of resting-state networks in mice using high-frame rate functional ultrasound

K Hikishima, T Tsurugizawa, K Kasahara, R Takagi… - NeuroImage, 2023 - Elsevier
Functional ultrasound (fUS) imaging is a method for visualizing deep brain activity based on
cerebral blood volume changes coupled with neural activity, while functional MRI (fMRI) …

Transcranial focused ultrasound selectively increases perfusion and modulates functional connectivity of deep brain regions in humans.

N Spivak, B Dang, S Becerra, S Halavi, N Rotstein… - 2023 - escholarship.org
BACKGROUND: Low intensity, transcranial focused ultrasound (tFUS) is a re-emerging
brain stimulation technique with the unique capability of reaching deep brain structures non …