Different phylotypes of Cutibacterium acnes cause different modic changes in intervertebral disc degeneration
W Lan, X Wang, X Tu, X Hu, H Lu - PloS one, 2022 - journals.plos.org
Background The contribution of Cutibacterium acnes (C. acnes) infection to intervertebral
disc degeneration (IDD) and the antibiotic therapy has evoked several controversies in …
disc degeneration (IDD) and the antibiotic therapy has evoked several controversies in …
“Are we barking up the wrong tree? Too much emphasis on Cutibacterium acnes and ignoring other pathogens”—a study based on next-generation sequencing of …
S Rajasekaran, G Vasudevan, M Easwaran, ND Ps… - The Spine Journal, 2023 - Elsevier
BACKGROUND The majority of literature on bacterial flora in the disc stands disadvantaged
in utilizing traditional culture methods and targeting a single bacterium, Cutibacterium …
in utilizing traditional culture methods and targeting a single bacterium, Cutibacterium …
The Role of Cutibacterium acnes in Intervertebral Disc Inflammation
B Schmid, O Hausmann, W Hitzl, Y Achermann… - Biomedicines, 2020 - mdpi.com
Recently, the role of infection of the intervertebral disc (IVD) with Cutibacterium acnes (C.
acnes) as a contributor to disc-related low back pain (LBP) has been discussed. The aim of …
acnes) as a contributor to disc-related low back pain (LBP) has been discussed. The aim of …
Is the discopathy associated with Modic changes an infectious process? Results from a prospective monocenter study
S Ahmed-Yahia, JW Decousser… - PLoS …, 2019 - journals.plos.org
Background The local infectious origin and the putative role of Cutibacterium acnes (CA) of
a particular subtype of discopathy (Modic 1) are still debated. Purpose To establish the …
a particular subtype of discopathy (Modic 1) are still debated. Purpose To establish the …
Modic Changes and Disc Degeneration Caused by Inoculation of Propionibacterium acnes inside Intervertebral Discs of Rabbits: A Pilot Study
Z Chen, Y Zheng, Y Yuan, Y Jiao, J Xiao… - BioMed Research …, 2016 - Wiley Online Library
Purpose. To investigate whether P. acnes could induce disc degeneration and Modic
changes when inoculated into the discs of rabbits. Method. A wild‐type strain of P. acnes …
changes when inoculated into the discs of rabbits. Method. A wild‐type strain of P. acnes …
New contributions on chronic low back pain: disc infection or contaminated cultures?
MG Victoria, A Gimeno‐Gascón, MP Ventero… - Apmis, 2023 - Wiley Online Library
There is controversy about the likely infectious origin of chronic low back pain, because it
has been suggested the possibility of a relationship with infection by Cutibacterium acnes …
has been suggested the possibility of a relationship with infection by Cutibacterium acnes …
Would Cutibacterium acnes Be the Villain for the Chronicity of Low Back Pain in Degenerative Disc Disease? Preliminary Results of an Analytical Cohort
VM da Rocha, COGX Lima, GB Candido… - Journal of personalized …, 2023 - mdpi.com
In the last decade, several studies have demonstrated Cutibacterium acnes colonization in
intervertebral discs (IVDs) in patients with lumbar disc degeneration (LDD) and low back …
intervertebral discs (IVDs) in patients with lumbar disc degeneration (LDD) and low back …
Colonization of intervertebral discs by Cutibacterium acnes in patients with low back pain: Protocol for an analytical study with microbiological, phenotypic, genotypic …
V Magno da Rocha, COGX Lima, EO Ferreira… - Plos one, 2023 - journals.plos.org
Lumbar disc degeneration (LDD) and low back pain (LBP) are two conditions that are
closely related. Several studies have shown Cutibacterium acnes colonization of …
closely related. Several studies have shown Cutibacterium acnes colonization of …
Evidence for infection in intervertebral disc degeneration: a systematic review
I Granville Smith, NP Danckert, MB Freidin… - European Spine …, 2022 - Springer
Purpose Back pain is a major problem worldwide and is linked to intervertebral disc
degeneration and Modic change. Several studies report growth of bacteria following …
degeneration and Modic change. Several studies report growth of bacteria following …
Modic changes in the adjacent vertebrae due to disc material infection with Propionibacterium acnes in patients with lumbar disc herniation
J Aghazadeh, F Salehpour, E Ziaeii, N Javanshir… - European Spine …, 2017 - Springer
Abstract Introduction Modic changes (MCs) in vertebral bones are induced by two
mechanisms of mechanical factors and infection. As Propionibacterium acnes (P. acnes) …
mechanisms of mechanical factors and infection. As Propionibacterium acnes (P. acnes) …
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