[HTML][HTML] The human urine metabolome
S Bouatra, F Aziat, R Mandal, AC Guo, MR Wilson… - PloS one, 2013 - journals.plos.org
Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …
Challenges in metabolomics-based tests, biomarkers revealed by metabolomic analysis, and the promise of the application of metabolomics in precision medicine
A Di Minno, M Gelzo, M Caterino, M Costanzo… - International Journal of …, 2022 - mdpi.com
Metabolomics helps identify metabolites to characterize/refine perturbations of biological
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …
“Notame”: workflow for non-targeted LC–MS metabolic profiling
Metabolomics analysis generates vast arrays of data, necessitating comprehensive
workflows involving expertise in analytics, biochemistry and bioinformatics in order to …
workflows involving expertise in analytics, biochemistry and bioinformatics in order to …
NMR metabolomics of human blood and urine in disease research
This paper reviews the main applications of NMR metabolomics of blood and urine in
disease research, over the last 5 years. The broad range of disease types addressed attests …
disease research, over the last 5 years. The broad range of disease types addressed attests …
Metabolomics: an emerging but powerful tool for precision medicine
CB Clish - Molecular Case Studies, 2015 - molecularcasestudies.cshlp.org
Metabolomics, which is defined as the comprehensive analysis of metabolites in a biological
specimen, is an emerging technology that holds promise to inform the practice of precision …
specimen, is an emerging technology that holds promise to inform the practice of precision …
Recent advances in NMR-based metabolomics
GA Nagana Gowda, D Raftery - Analytical Chemistry, 2017 - ACS Publications
NMR spectroscopy, one of the two major analytical platforms utilized in the metabolomics
field, has witnessed a large number of advances in fundamental studies, methods …
field, has witnessed a large number of advances in fundamental studies, methods …
Interlaboratory reproducibility of a targeted metabolomics platform for analysis of human serum and plasma
A critical question facing the field of metabolomics is whether data obtained from different
centers can be effectively compared and combined. An important aspect of this is the …
centers can be effectively compared and combined. An important aspect of this is the …
Exploring disease through metabolomics
N Vinayavekhin, EA Homan… - ACS chemical biology, 2010 - ACS Publications
Metabolomics approaches provide an analysis of changing metabolite levels in biological
samples. In the past decade, technical advances have spurred the application of …
samples. In the past decade, technical advances have spurred the application of …
Large-scale targeted metabolomics method for metabolite profiling of human samples
G Cao, Z Song, Y Hong, Z Yang, Y Song, Z Chen… - Analytica Chimica …, 2020 - Elsevier
Targeted metabolomics has significant advantages for quantification but suffers from
reduced metabolite coverage. In this study, we developed a large-scale targeted …
reduced metabolite coverage. In this study, we developed a large-scale targeted …
Recent and potential developments of biofluid analyses in metabolomics
A Zhang, H Sun, P Wang, Y Han, X Wang - Journal of proteomics, 2012 - Elsevier
Metabolomics, one of the 'omic'sciences in systems biology, is the global assessment and
validation of endogenous small-molecule metabolites within a biologic system. Analysis of …
validation of endogenous small-molecule metabolites within a biologic system. Analysis of …