In eutherian mammals, the first cell types that are specified during embryogenesis are
committed to form extraembryonic (placenta and fetal membranes) rather than embryonic …

According to Lewis Wolpert,“It is not birth, marriage or death, but gastrulation which is truly
the most important time in your life”(quoted in Slack, 1983). While it is certainly true that …

The process of placentation in vertebrate species is remarkably morphologically diverse.
The types of placentae formed range from the epitheliochorial, where the maternal uterine …

Background Fetal membrane development varies greatly across mammals with significant
implications for models of human placentation. Method Therefore the major patterns of fetal …

A cell line was derived from midgestation chorioallantoic placental explants of the outbred
Holtzman rat. The cell line was found to express characteristics of extraembryonic …

The placenta is comprised of an inner vascular network covered by an outer epithelium,
called trophoblast, all designed to promote the delivery of nutrients to the fetus. Several …

Growth, differentiation and morphogenesis during the early development of amniotic
vertebrates are concerned primarily with the establishment of a system of extraembryonic …

The trophectoderm epithelium is the first tissue to differentiate during mammalian
development. It constitutes the wall of the spherical blastocyst and, after implantation, is the …

The word placenta is derived from the Latin term meaning 'flat cake'. Despite the rather
humble name, the placenta is an amazing organ that forms both the interface for selective …

Specification of the trophoblast cell lineage comprising the outermost epithelial cell layer of
the blastocyst occurs early in development and is a prerequisite for implantation of the …