A guide to regulation of the formation of biomolecular condensates
A Bratek‐Skicki, R Pancsa, B Meszaros… - The FEBS …, 2020 - Wiley Online Library
Cellular organelles that lack a surrounding lipid bilayer, such as the nucleolus and stress
granule, represent a newly recognized, general paradigm of cellular organization. The …
granule, represent a newly recognized, general paradigm of cellular organization. The …
A platform to induce and mature biomolecular condensates using chemicals and light
CN Hernandez-Candia, BR Brady, E Harrison… - Nature Chemical …, 2024 - nature.com
Biomolecular condensates are membraneless compartments that impart spatial and
temporal organization to cells. Condensates can undergo maturation, transitioning from …
temporal organization to cells. Condensates can undergo maturation, transitioning from …
Synthetic protein condensates that inducibly recruit and release protein activity in living cells
M Yoshikawa, T Yoshii, M Ikuta… - Journal of the American …, 2021 - ACS Publications
Compartmentation of proteins into biomolecular condensates or membraneless organelles
formed by phase separation is an emerging principle for the regulation of cellular processes …
formed by phase separation is an emerging principle for the regulation of cellular processes …
Interface of biomolecular condensates modulates redox reactions
Biomolecular condensates mediate diverse cellular processes. The density-transition
process of condensate formation results in the selective partitioning of molecules, which …
process of condensate formation results in the selective partitioning of molecules, which …
Phase separation of intrinsically disordered proteins
There is growing interest in the topic of intracellular phase transitions that lead to the
formation of biologically regulated biomolecular condensates. These condensates are …
formation of biologically regulated biomolecular condensates. These condensates are …
[HTML][HTML] Who's in and who's out—compositional control of biomolecular condensates
Biomolecular condensates are two-and three-dimensional compartments in eukaryotic cells
that concentrate specific collections of molecules without an encapsulating membrane …
that concentrate specific collections of molecules without an encapsulating membrane …
[HTML][HTML] Designer condensates: a toolkit for the biomolecular architect
RL Hastings, S Boeynaems - Journal of Molecular Biology, 2021 - Elsevier
Protein phase separation has emerged as a novel paradigm to explain the biogenesis of
membraneless organelles and other so-called biomolecular condensates. While the …
membraneless organelles and other so-called biomolecular condensates. While the …
Controlling compartmentalization by non-membrane-bound organelles
RJ Wheeler, AA Hyman - Philosophical Transactions of …, 2018 - royalsocietypublishing.org
Compartmentalization is a characterizing feature of complexity in cells, used to organize
their biochemistry. Membrane-bound organelles are most widely known, but non-membrane …
their biochemistry. Membrane-bound organelles are most widely known, but non-membrane …
Liquid–liquid phase separation in disease
S Alberti, D Dormann - Annual review of genetics, 2019 - annualreviews.org
We have made rapid progress in recent years in identifying the genetic causes of many
human diseases. However, despite this recent progress, our mechanistic understanding of …
human diseases. However, despite this recent progress, our mechanistic understanding of …
A brief guideline for studies of phase-separated biomolecular condensates
Y Gao, X Li, P Li, Y Lin - Nature Chemical Biology, 2022 - nature.com
Cells are exquisitely compartmentalized to achieve precise spatiotemporal regulation of
myriad processes and pathways. Phase separation offers one way to achieve territorial …
myriad processes and pathways. Phase separation offers one way to achieve territorial …