Cellular organelles that lack a surrounding lipid bilayer, such as the nucleolus and stress
granule, represent a newly recognized, general paradigm of cellular organization. The …

Biomolecular condensates are membraneless compartments that impart spatial and
temporal organization to cells. Condensates can undergo maturation, transitioning from …

Compartmentation of proteins into biomolecular condensates or membraneless organelles
formed by phase separation is an emerging principle for the regulation of cellular processes …

Biomolecular condensates mediate diverse cellular processes. The density-transition
process of condensate formation results in the selective partitioning of molecules, which …

There is growing interest in the topic of intracellular phase transitions that lead to the
formation of biologically regulated biomolecular condensates. These condensates are …

Biomolecular condensates are two-and three-dimensional compartments in eukaryotic cells
that concentrate specific collections of molecules without an encapsulating membrane …

Protein phase separation has emerged as a novel paradigm to explain the biogenesis of
membraneless organelles and other so-called biomolecular condensates. While the …

Compartmentalization is a characterizing feature of complexity in cells, used to organize
their biochemistry. Membrane-bound organelles are most widely known, but non-membrane …

We have made rapid progress in recent years in identifying the genetic causes of many
human diseases. However, despite this recent progress, our mechanistic understanding of …

Cells are exquisitely compartmentalized to achieve precise spatiotemporal regulation of
myriad processes and pathways. Phase separation offers one way to achieve territorial …