A fast and accurate way to determine short chain fatty acids in mouse feces based on GC–MS

X Han, J Guo, Y You, M Yin, C Ren, J Zhan… - … of Chromatography B, 2018 - Elsevier
Short-chain fatty acids (SCFAs) in the gut are mainly produced by the anaerobic microbial
fermentation of unabsorbed dietary carbohydrates in the large bowel. Quantitative …

Development and validation of a GC-FID method for the analysis of short chain fatty acids in rat and human faeces and in fermentation fluids

S Scortichini, MC Boarelli, S Silvi, D Fiorini - Journal of Chromatography B, 2020 - Elsevier
Short-chain fatty acids (SCFAs) are gut microbiota metabolites recognized for their beneficial
effects on the host organism. In this study, a simple and rapid sample preparation method …

Accurate and reliable quantitation of short chain fatty acids from human feces by ultra high-performance liquid chromatography-high resolution mass spectrometry …

L Chen, X Sun, AS Khalsa, MT Bailey… - … of pharmaceutical and …, 2021 - Elsevier
Short chain fatty acids (SCFAs), generated from microbial fermentation of dietary fibers, can
regulate weight, appetite and energy homeostasis. Therefore, measuring SCFAs in fecal …

A rapid and convenient derivatization method for quantitation of short‐chain fatty acids in human feces by ultra‐performance liquid chromatography/tandem mass …

H Fu, Q Zhang, X Huang, Z Ma, X Zheng… - Rapid …, 2020 - Wiley Online Library
Rationale Short‐chain fatty acids (SCFAs) are associated with intestinal microbiota and
diseases in humans. SCFAs have a low response in mass spectrometry, and in order to …

Freeze-drying enables homogeneous and stable sample preparation for determination of fecal short-chain fatty acids

J Ueyama, M Oda, M Hirayama, K Sugitate, N Sakui… - Analytical …, 2020 - Elsevier
Background The analysis methods for fecal short-chain fatty acids (SCFAs) have evolved
considerably. Recently, the role of SCFAs in gastrointestinal physiology and their …

Analysis of short-chain fatty acids in human feces: a scoping review

M Primec, D Mičetić-Turk, T Langerholc - Analytical biochemistry, 2017 - Elsevier
Short-chain fatty acids (SCFAs) play a crucial role in maintaining homeostasis in humans,
therefore the importance of a good and reliable SCFAs analytical detection has raised a lot …

Evaluation and optimization of sample handling methods for quantification of short-chain fatty acids in human fecal samples by GC–MS

YL Hsu, CC Chen, YT Lin, WK Wu… - Journal of proteome …, 2019 - ACS Publications
The gut microbiota has attracted a great deal of interest in recent years due to its association
with many diseases. Short-chain fatty acids (SCFAs), the end products of dietary fiber …

An isotope-labeled chemical derivatization method for the quantitation of short-chain fatty acids in human feces by liquid chromatography–tandem mass spectrometry

J Han, K Lin, C Sequeira, CH Borchers - Analytica chimica acta, 2015 - Elsevier
Short-chain fatty acids (SCFAs) are produced by anaerobic gut microbiota in the large
bowel. Qualitative and quantitative measurements of SCFAs in the intestinal tract and the …

Quantification of fecal short chain fatty acids by liquid chromatography tandem mass spectrometry—investigation of pre-analytic stability

G Liebisch, J Ecker, S Roth, S Schweizer, V Öttl… - Biomolecules, 2019 - mdpi.com
Short chain fatty acids (SCFAs) are generated by the degradation and fermentation of
complex carbohydrates,(ie, dietary fiber) by the gut microbiota relevant for microbe–host …

Rapid profiling method for mammalian feces short chain fatty acids by GC-MS

T Furuhashi, K Sugitate, T Nakai, Y Jikumaru… - Analytical …, 2018 - Elsevier
Short chain fatty acids (SCFAs) are key feces metabolites generated by gut bacteria
fermentation. Despite the importance of profiling feces SCFAs, technical difficulties in …