Extreme obesity—also referred to as severe, grade III, or morbid obesity—is defined as a
body mass index (BMI)> 40 kg/m2, and occurs in 7.7% of the adult US population. 1 This …

Purpose: There is limited clinical data evaluating anticoagulation with the direct oral
anticoagulants (DOACs) in morbidly obese patients. We sought to examine the efficacy in …

Although patients suffering from atrial fibrillation have increased worldwide, detailed
information about factors associated with bleeding during direct oral anticoagulant therapy …

The present study aimed to assess the associations between dosing of DOACs and
outcomes in patients with non-valvular atrial fibrillation (NVAF). Direct oral anticoagulants …

This sub-analysis of the XAPASS, a prospective, single-arm, observational study, aimed to
evaluate relationships between body mass index (BMI) and safety (major bleeding and all …

Anticoagulation therapy is recommended for patients with non-valvular atrial fibrillation
(NVAF) and an increased risk of stroke. Although apixaban showed superiority over warfarin …

Direct oral anticoagulants (DOACs) have been demonstrated to be more effective and safer
than vitamin-K antagonist (VKA) for stroke prevention in patients with nonvalvular atrial …

Abstract Purpose of Review The purpose of this review is to examine the safety and
effectiveness of direct oral anticoagulants and provide recommendations for the treatment of …

Atrial fibrillation (AF) is the most common cardiac arrhythmia and the incidence and
prevalence of this disease are rising. 1 2 It is estimated that by the year 2050 there will be …

Background: Studies indicate that women with atrial fibrillation (AF) are less likely to receive
anticoagulants despite their higher risk of stroke compared with men. Objective: To evaluate …