Direct oral anticoagulant use in special populations: elderly, obesity, and renal failure

EM White, JC Coons - Current Cardiology Reports, 2021 - Springer
Abstract Purpose of Review The purpose of this review is to examine the safety and
effectiveness of direct oral anticoagulants and provide recommendations for the treatment of …

Gender differences in efficacy and safety of direct oral anticoagulants in atrial fibrillation: systematic review and network meta-analysis

BH Raccah, A Perlman, DR Zwas… - Annals of …, 2018 - journals.sagepub.com
Background: Studies indicate that women with atrial fibrillation (AF) are less likely to receive
anticoagulants despite their higher risk of stroke compared with men. Objective: To evaluate …

[HTML][HTML] Efficacy and safety of direct oral anticoagulants in patients with atrial fibrillation and high thromboembolic risk. A systematic review

D Acanfora, MM Ciccone, P Scicchitano… - Frontiers in …, 2019 - frontiersin.org
Background: The aim of the study was to evaluate the efficacy and safety of direct oral
anticoagulants (DOACs) in a subgroup of patients with atrial fibrillation (AF), CHADS2 …

[HTML][HTML] Efficacy and safety of non-recommended dose of new oral anticoagulants in patients with atrial fibrillation: a systematic review and meta-analysis

X Kong, Y Zhu, L Pu, S Meng, L Zhao… - Frontiers in …, 2021 - frontiersin.org
Introduction: The real-world treatment of atrial fibrillation (AF) often involves the prescription
of new oral anticoagulants (NOACs) using dosing both lower and higher than recommended …

Effect of non‐recommended doses versus recommended doses of direct oral anticoagulants in atrial fibrillation patients: A meta‐analysis

X Liu, M Huang, C Ye, X Xiao, C Yan - Clinical Cardiology, 2021 - Wiley Online Library
Background Several observational studies have shown that the inappropriate dosing use of
direct oral anticoagulants (DOACs) in atrial fibrillation (AF) that does not conform to …

Sex-related difference in bleeding and thromboembolic risks in patients with atrial fibrillation treated with direct oral anticoagulants

M Matsumura, Y Sotomi, A Hirata, Y Sakata… - Heart and Vessels, 2022 - Springer
Background: Sex-related difference in non-valvular atrial fibrillation (NVAF) patients treated
with direct oral anticoagulants (DOACs) is still to be investigated. We aimed to investigate …

DOAC compared with warfarin for VTE in patients with obesity: a retrospective cohort study conducted through the VENUS network

KA Martin, N Lancki, C Li, ME Eyster… - Journal of thrombosis …, 2023 - Springer
The effectiveness and safety of direct oral anticoagulants (DOAC) compared with warfarin
remains uncertain in obese patients. We assessed the comparative effectiveness and safety …

Impact of direct oral anticoagulant off‐label doses on clinical outcomes of atrial fibrillation patients: a systematic review

J Santos, N António, M Rocha… - British Journal of Clinical …, 2020 - Wiley Online Library
Aims Worldwide observational studies are evidencing discordance between guidelines and
real‐world practice regarding direct oral anticoagulant drug (DOAC) doses. This systematic …

[HTML][HTML] Effectiveness and safety of direct oral anticoagulants among patients with non-valvular atrial fibrillation and multimorbidity

AD Dhamane, M Ferri, A Keshishian, C Russ… - Advances in …, 2023 - Springer
Introduction In the USA, there is a steady rise of atrial fibrillation due to the aging population
with increased morbidity. This study evaluated the risk of stroke/systemic embolism (S/SE) …

[HTML][HTML] Direct oral anticoagulants for the prevention of stroke in patients with nonvalvular atrial fibrillation: understanding differences and similarities

PP Dobesh, J Fanikos - Drugs, 2015 - Springer
The presence of atrial fibrillation (AF), the most common sustained cardiac arrhythmia,
significantly increases the risk for stroke. Current guidelines recommend that the vitamin K …