Suboptimal use of oral anticoagulants in atrial fibrillation: has the introduction of direct oral anticoagulants improved prescribing practices?

EA Alamneh, L Chalmers, LR Bereznicki - American journal of …, 2016 - Springer
Abstract Background and Objectives Atrial fibrillation (AF) and the associated risk of stroke
are emerging epidemics throughout the world. Suboptimal use of oral anticoagulants for …

Efficacy and safety of novel oral anticoagulants in patients with atrial nonvalvular atrial fibrillation and diabetes mellitus: a systematic review and meta-analysis

X Jia, Z Yin, W Zhang, S Du, J Kang - Journal of Translational Medicine, 2022 - Springer
Objective This study incorporates the results of subgroup analyses of currently published
randomized controlled trials (RCTs) and real-world cohort studies to compare the …

Risks and benefits of oral anticoagulants for stroke prophylaxis in atrial fibrillation according to body mass index: nationwide cohort study of primary care records in …

YM Nakao, K Nakao, J Wu, R Nadarajah… - …, 2022 - thelancet.com
Summary Background Direct oral anticoagulants (DOACs) are effective and safe alternatives
to warfarin for stroke prophylaxis for atrial fibrillation (AF). Whether this extends to patients at …

Reduced dose direct oral anticoagulants compared with warfarin with high time in therapeutic range in nonvalvular atrial fibrillation

M Jansson, S Själander, V Sjögren, F Björck… - Journal of Thrombosis …, 2023 - Springer
Direct oral anticoagulants (DOACs) used in nonvalvular atrial fibrillation (NVAF) are dose-
reduced in elderly and patients with impaired renal function. Only reduced dose dabigatran …

Meta-analysis of direct-acting oral anticoagulants compared with warfarin in patients> 75 years of age

AH Malik, S Yandrapalli, WS Aronow, JA Panza… - The American journal of …, 2019 - Elsevier
Older patients with atrial fibrillation (AF) are at higher risk of thromboembolic events and oral
anticoagulant (OAC)-related bleeding complications. This meta-analysis evaluates the …

Efficacy and safety of apixaban versus warfarin in patients with atrial fibrillation and extremes in body weight: insights from the ARISTOTLE trial

SH Hohnloser, M Fudim, JH Alexander, DM Wojdyla… - Circulation, 2019 - Am Heart Assoc
Background: Guidelines caution against the use of non–vitamin K antagonist oral
anticoagulants in patients with extremely high (> 120 kg) or low (≤ 60 kg) body weight …

[HTML][HTML] A systematic review of network meta-analyses among patients with nonvalvular atrial fibrillation: a comparison of efficacy and safety following treatment with …

AT Cohen, NR Hill, X Luo, C Masseria… - International journal of …, 2018 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) are indicated for the prevention of
stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation. While no …

Systematic review and adjusted indirect comparison meta-analysis of oral anticoagulants in atrial fibrillation

WL Baker, OJ Phung - Circulation: Cardiovascular Quality and …, 2012 - Am Heart Assoc
Background—Oral anticoagulants such as apixaban, dabigatran, and rivaroxaban are
alternatives to warfarin for preventing events in patients with atrial fibrillation. Direct …

Off-label dose direct oral anticoagulants and clinical outcomes in Asian patients with atrial fibrillation: a new evidence of Asian dose

W Xu, M Lv, T Wu, N Huang, W Zhang, J Su… - International Journal of …, 2023 - Elsevier
Aim This study aimed to evaluate the label compliance of DOACs in the Chinese AF
population and explore the relationship between inappropriate DOACs dosage and clinical …

Obesity paradox in atrial fibrillation: implications for outcomes and relationship with oral anticoagulant drugs

M Proietti, G Boriani - American Journal of Cardiovascular Drugs, 2020 - Springer
In the last 40 years, concern about the obesity epidemic has increased. Data from the
current literature highlight a strong relationship between obesity and atrial fibrillation (AF) …