[HTML][HTML] Biological role of metabolic reprogramming of cancer cells during epithelial‑mesenchymal transition

M Li, X Bu, B Cai, P Liang, K Li, X Qu… - Oncology …, 2019 - spandidos-publications.com
Epithelial‑mesenchymal transition (EMT) is required for the distant metastasis of tumors. The
degree of tumor malignancy increases as EMT progresses. Notably, the biology of tumor …

[HTML][HTML] Role of metabolic reprogramming in epithelial–mesenchymal transition (EMT)

H Kang, H Kim, S Lee, HS Youn, BH Youn - International Journal of …, 2019 - mdpi.com
Activation of epithelial–mesenchymal transition (EMT) is thought to be an essential step for
cancer metastasis. Tumor cells undergo EMT in response to a diverse range of extra-and …

[HTML][HTML] Metabolic reprogramming and epithelial-mesenchymal plasticity: opportunities and challenges for cancer therapy

NY Sun, MH Yang - Frontiers in oncology, 2020 - frontiersin.org
Metabolic reprogramming and epithelial-mesenchymal plasticity are both hallmarks of the
adaptation of cancer cells for tumor growth and progression. For metabolic changes, cancer …

[HTML][HTML] Targeting the metabolic reprogramming that controls epithelial-to-mesenchymal transition in aggressive tumors

A Morandi, ML Taddei, P Chiarugi, E Giannoni - Frontiers in oncology, 2017 - frontiersin.org
The epithelial-to-mesenchymal transition (EMT) process allows the trans-differentiation of a
cell with epithelial features into a cell with mesenchymal characteristics. This process has …

[HTML][HTML] Interplay between metabolism reprogramming and epithelial-to-mesenchymal transition in cancer stem cells

Y Daniel, E Lelou, C Aninat, A Corlu, F Cabillic - Cancers, 2021 - mdpi.com
Simple Summary Tumor cells display important plasticity potential. Notably, tumor cells have
the ability to change toward immature cells called cancer stem cells under the influence of …

Metabolism within the tumor microenvironment and its implication on cancer progression: An ongoing therapeutic target

MC Ocaña, B Martínez‐Poveda… - Medicinal research …, 2019 - Wiley Online Library
Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor
metabolism is again in the spotlight of cancer research. Many studies have been carried out …

[HTML][HTML] Metabolism in cancer stem cells: targets for clinical treatment

GM Wen, XY Xu, P Xia - Cells, 2022 - mdpi.com
Cancer stem cells (CSCs) have high tumorigenicity, high metastasis and high resistance to
treatment. They are the key factors for the growth, metastasis and drug resistance of …

[HTML][HTML] Linking metabolic reprogramming, plasticity and tumor progression

O Shuvalov, A Daks, O Fedorova, A Petukhov, N Barlev - Cancers, 2021 - mdpi.com
Simple Summary In the present review, we discuss the role of metabolic reprogramming
which occurs in malignant cells. The process of metabolic reprogramming is also known as …

[HTML][HTML] TGFβ-induced metabolic reprogramming during epithelial-to-mesenchymal transition in cancer

W Hua, P Ten Dijke, S Kostidis, M Giera… - Cellular and Molecular …, 2020 - Springer
Metastasis is the most frequent cause of death in cancer patients. Epithelial-to-mesenchymal
transition (EMT) is the process in which cells lose epithelial integrity and become motile, a …

Metabolic reprogramming in cancer: Mechanisms and therapeutics

S Nong, X Han, Y Xiang, Y Qian, Y Wei, T Zhang… - MedComm, 2023 - Wiley Online Library
Cancer cells characterized by uncontrolled growth and proliferation require altered
metabolic processes to maintain this characteristic. Metabolic reprogramming is a process …