It is known that the hippocampus has vital functions in learning and memory, behavioral
regulation, and activity-dependent synaptic plasticity, and that the hippocampus contains …

The involvement of the changed expression/function of neurotrophic factors in the
pathogenesis of neurodegenerative diseases, including Alzheimer's disease (AD), has been …

The function of the brain-derived neurotrophic factor (BDNF) via activation through its high-
affinity receptor Tropomyosin receptor kinase B (TrkB) has a pivotal role in cell …

Given that brain-derived neutrophic factor (BDNF) modulates both short-term synaptic
function and activity-dependent synaptic plasticity in the adult hippocampus, here we …

Alzheimer's disease (AD) is generally defined as the aberrant production of β-amyloid
protein (Aβ) and hyperphosphorylated tau protein, which are deposited in β-amyloid …

Brain-derived neurotrophic factor (BDNF) is regarded as an important factor for
neurogenesis, synaptic plasticity, and neuronal network organization in brain circuits …

Late adulthood is associated with increased hippocampal atrophy and dysfunction. Although
there are multiple paths by which hippocampal deterioration occurs in late life, the authors …

The oligomeric form of the amyloid peptide Aβ 1–42 is capable of perturbing synaptic
plasticity in different brain areas. Here, we evaluated the protective role of brain-derived …

Damage occurring to noradrenergic neurons in the locus coeruleus (LC) contributes to the
evolution of neuroinflammation and neurodegeneration in a variety of conditions and …

Decreased expression of brain-derived neurotrophic factor (BDNF) plays an important role
in the pathogenesis of Alzheimer's disease, and a typical pathological change in Alzheimer's …