Emphasizing roles of BDNF promoters and inducers in Alzheimer's disease for improving impaired cognition and memory
M Banerjee, RR Shenoy - Journal of Basic and Clinical Physiology …, 2023 - degruyter.com
Brain-derived neurotrophic factor (BDNF) is a crucial neurotrophic factor adding to neurons'
development and endurance. The amount of BDNF present in the brain determines …
development and endurance. The amount of BDNF present in the brain determines …
Effect of the brain‐derived neurotrophic factor and the apolipoprotein E polymorphisms on disease progression in preclinical Alzheimer's disease
R Hashimoto, Y Hirata, T Asada… - Genes, Brain and …, 2009 - Wiley Online Library
Genetic factors, such as apolipoprotein E (ApoE) polymorphisms, are thought to play an
important role in the etiology of Alzheimer's disease (AD). Recent association studies have …
important role in the etiology of Alzheimer's disease (AD). Recent association studies have …
Transduced PTD-BDNF fusion protein protects against beta amyloid peptide-induced learning and memory deficits in mice
JP Zhou, ZG Feng, BL Yuan, SZ Yu, Q Li, HY Qu… - Brain research, 2008 - Elsevier
Brain-derived neurotrophic factor (BDNF) promotes the survival and differentiation of
hippocampal, cortical, and basal forebrain cholinergic neurons. However, the efficacy of …
hippocampal, cortical, and basal forebrain cholinergic neurons. However, the efficacy of …
The role of CREB and BDNF in neurobiology and treatment of Alzheimer's disease
Alzheimer's disease (AD) is the most common form of dementia worldwide. β-amyloid
peptide (Aβ) is currently assumed to be the main cause of synaptic dysfunction and cognitive …
peptide (Aβ) is currently assumed to be the main cause of synaptic dysfunction and cognitive …
[HTML][HTML] The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
MF Egan, M Kojima, JH Callicott, TE Goldberg… - Cell, 2003 - cell.com
Brain-derived neurotrophic factor (BDNF) modulates hippocampal plasticity and
hippocampal-dependent memory in cell models and in animals. We examined the effects of …
hippocampal-dependent memory in cell models and in animals. We examined the effects of …
Amyloid‐beta induced changes in vesicular transport of BDNF in hippocampal neurons
B Seifert, R Eckenstaler, R Rönicke, J Leschik… - Neural …, 2016 - Wiley Online Library
The neurotrophin brain derived neurotrophic factor (BDNF) is an important growth factor in
the CNS. Deficits in transport of this secretory protein could underlie neurodegenerative …
the CNS. Deficits in transport of this secretory protein could underlie neurodegenerative …
A novel polymorphism of the brain-derived neurotrophic factor (BDNF) gene associated with late-onset Alzheimer's disease
H Kunugi, A Ueki, M Otsuka, K Isse, H Hirasawa… - Molecular …, 2001 - nature.com
Several lines of evidence have suggested altered functions of the brain-derived
neurotrophic factor (BDNF) in the pathogenesis of neurodegenerative diseases including …
neurotrophic factor (BDNF) in the pathogenesis of neurodegenerative diseases including …
Difference in methylation and expression of brain-derived neurotrophic factor in Alzheimer's disease and mild cognitive impairment
K Kouter, M Nikolac Perkovic, G Nedic Erjavec, T Milos… - Biomedicines, 2023 - mdpi.com
Due to the increasing number of progressive dementias in the population, numerous studies
are being conducted that seek to determine risk factors, biomarkers and pathological …
are being conducted that seek to determine risk factors, biomarkers and pathological …
Variations in the BDNF Gene in Autopsy-Confirmed Alzheimer's Disease and Dementia with Lewy Bodies in Japan
H Akatsu, HD Yamagata, J Kawamata… - Dementia and geriatric …, 2006 - karger.com
Abstract Background/Aim: Brain-derived neurotrophic factor (BDNF) is associated with the
hippocampus and the nigrostriatal dopaminergic function. Data showing that its level was …
hippocampus and the nigrostriatal dopaminergic function. Data showing that its level was …
Amyloid β serves as an NGF‐like neurotrophic factor or acts as a NGF antagonist depending on its concentration
MÁ Arevalo, PM Roldan, PJ Chacón… - Journal of …, 2009 - Wiley Online Library
In the nervous system, both the shape and connectivity of neurons are strongly influenced by
soluble, extracellular factors. Indeed, we recently demonstrated that after binding to …
soluble, extracellular factors. Indeed, we recently demonstrated that after binding to …