Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an …
O Carretón, A Giralt, JF Torres-Peraza, V Brito… - Experimental …, 2012 - Elsevier
Brain-derived neurotrophic factor (BDNF) is a key player in learning and memory processes.
However, little is known about brain area-specific functions of this neurotrophin. Here we …
However, little is known about brain area-specific functions of this neurotrophin. Here we …
Dynamics of myelin deficits in the 5xFAD mouse model for Alzheimer's disease and the protective role of BDNF
I Zota, K Chanoumidou, I Charalampopoulos… - Glia, 2024 - Wiley Online Library
Recent findings highlight myelin breakdown as a decisive early event in Alzheimer's
Disease (AD) acting as aggravating factor of its progression. However, it is still unclear …
Disease (AD) acting as aggravating factor of its progression. However, it is still unclear …
[HTML][HTML] Brain-derived neurotrophic factor: a key molecule for memory in the healthy and the pathological brain
M Miranda, JF Morici, MB Zanoni… - Frontiers in cellular …, 2019 - frontiersin.org
Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes
related to learning and memory. The expression of BDNF is highly regulated, and can lead …
related to learning and memory. The expression of BDNF is highly regulated, and can lead …
DNA methylation and tag SNPs of the BDNF gene in conversion of amnestic mild cognitive impairment into Alzheimer's disease: a cross-sectional cohort study
B Xie, Z Liu, W Liu, L Jiang, R Zhang… - Journal of …, 2017 - content.iospress.com
Alzheimer's disease (AD) is a complex multifactorial disease influenced by both genetic and
epigenetic factors. This study was aimed to evaluate the interaction between brain-derived …
epigenetic factors. This study was aimed to evaluate the interaction between brain-derived …
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease
AH Nagahara, DA Merrill, G Coppola, S Tsukada… - Nature medicine, 2009 - nature.com
Profound neuronal dysfunction in the entorhinal cortex contributes to early loss of short-term
memory in Alzheimer's disease,,. Here we show broad neuroprotective effects of entorhinal …
memory in Alzheimer's disease,,. Here we show broad neuroprotective effects of entorhinal …
BDNF and memory processing
Brain-derived neurotrophic factor has emerged as one of the most important molecules
involved in memory. Its wide role in different types of memories that depend on different …
involved in memory. Its wide role in different types of memories that depend on different …
Lysosomal dysfunction reduces brain-derived neurotrophic factor expression
E Bednarski, JC Lauterborn, CM Gall, G Lynch - Experimental neurology, 1998 - Elsevier
Brain-derived neurotrophic factor (BDNF) expression in hippocampus and cortex is
considerably reduced in Alzheimer's disease. The present study tested if lysosomal …
considerably reduced in Alzheimer's disease. The present study tested if lysosomal …
Female-specific effect of the BDNF gene on Alzheimer's disease
Alzheimer's disease (AD) is the most common neurodegenerative disease influenced by
genetic and environmental factors. Brain-derived neurotrophic factor (BDNF) plays an …
genetic and environmental factors. Brain-derived neurotrophic factor (BDNF) plays an …
Immunohistochemical study of the hnRNP A2 and B1 in the hippocampal formations of brains with Alzheimer's disease
K Mizukami, M Ishikawa, M Iwakiri, MD Ikonomovic… - Neuroscience …, 2005 - Elsevier
To elucidate the post-transcriptional regulation in the subjects with Alzheimer's disease
(AD), we employed immunohistochemical techniques and examined the expression of the …
(AD), we employed immunohistochemical techniques and examined the expression of the …
Conditional BDNF delivery from astrocytes rescues memory deficits, spine density, and synaptic properties in the 5xFAD mouse model of Alzheimer disease
B de Pins, C Cifuentes-Díaz, AT Farah… - Journal of …, 2019 - Soc Neuroscience
It has been well documented that neurotrophins, including brain-derived neurotrophic factor
(BDNF), are severely affected in Alzheimer's disease (AD), but their administration faces a …
(BDNF), are severely affected in Alzheimer's disease (AD), but their administration faces a …