Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease that causes
damage to multiple organ systems. Despite decades of research and available murine …

Systemic lupus erythematosus (SLE) represents a challenging autoimmune disease from a
clinical perspective because of its varied forms of presentation. Although broad-spectrum …

Systemic lupus erythematosus (SLE) is an autoimmune disorder that is characterized by
autoantibody production and dysregulated immune cell activation. Although the exact …

Our understanding of the genetic basis of systemic lupus erythematosus (SLE) has been
rapidly advanced using large-scale, case–control, candidate gene studies as well as …

Our understanding of the genetic basis of systemic lupus erythematosus has progressed
rapidly in recent years. While many genetic polymorphisms have been associated with …

Genome-wide association studies and fine mapping of candidate regions have rapidly
advanced our understanding of the genetic basis of systemic lupus erythematosus (SLE) …

We are currently witnessing an explosion of information about the genetic contribution to
complex human diseases such as systemic lupus erythematosus (SLE). These genetic …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of complex etiology
that primarily affects women of childbearing age. The development of SLE is attributed to the …

Abstract Purpose of Review Our understanding on genetic basis of SLE has been advanced
through genome-wide association studies. We review recent progress in lupus genetics with …

Systemic lupus erythematosus (SLE) is a polygenic chronic autoimmune disease leading to
multiple organ damage. A large heritability of up to 66% is estimated in SLE, with roughly …