Deciphering the Epigenetic Landscape: Placental Development and Its Role in Pregnancy Outcomes
Y Chen, Z Ye, M Lin, L Zhu, L Xu, X Wang - Stem Cell Reviews and …, 2024 - Springer
The placenta stands out as a unique, transitory, and multifaceted organ, essential to the
optimal growth and maturation of the fetus. Functioning as a vital nexus between the …
optimal growth and maturation of the fetus. Functioning as a vital nexus between the …
Single-cell RNA-seq revealed diverse cell types in the mouse placenta at mid-gestation
X Zhou, Y Xu, S Ren, D Liu, N Yang, Q Han… - Experimental Cell …, 2021 - Elsevier
The mammalian placenta consists of a set of cells to ensure normal placental functions
throughout gestation. Dysfunctional placentae are considered as the origin of a series of …
throughout gestation. Dysfunctional placentae are considered as the origin of a series of …
Placental transcriptome co-expression analysis reveals conserved regulatory programs across gestation
Background Mammalian development in utero is absolutely dependent on proper placental
development, which is ultimately regulated by the placental genome. The regulation of the …
development, which is ultimately regulated by the placental genome. The regulation of the …
Placental pathologic changes associated with fetal growth restriction and consequent neonatal outcomes
D Hwa Im, YN Kim, HJ Cho, YH Park… - Fetal and Pediatric …, 2021 - Taylor & Francis
Objective To evaluate the pathological changes of the placenta to determine the mechanism
underlying placenta-derived fetal growth restriction (FGR) and investigate its influence on …
underlying placenta-derived fetal growth restriction (FGR) and investigate its influence on …
The placenta: epigenetic insights into trophoblast developmental models of a generation-bridging organ with long-lasting impact on lifelong health
M Hemberger, W Dean - Physiological Reviews, 2023 - journals.physiology.org
The placenta is a unique organ system that functionally combines both maternal and fetal
cell types with distinct lineage origins. Normal placentation is critical for developmental …
cell types with distinct lineage origins. Normal placentation is critical for developmental …
Mid-gestational gene expression profile in placenta and link to pregnancy complications
Despite the importance of placenta in mediating rapid physiological changes in pregnancy,
data on temporal dynamics of placental gene expression are limited. We completed the first …
data on temporal dynamics of placental gene expression are limited. We completed the first …
Revealing the molecular landscape of human placenta: a systematic review and meta-analysis of single-cell RNA sequencing studies
BACKGROUND With increasing significance of developmental programming effects
associated with placental dysfunction, more investigations are devoted to improving the …
associated with placental dysfunction, more investigations are devoted to improving the …
Adaptability and potential for treatment of placental functions to improve embryonic development and postnatal health
JC Cross - Reproduction, Fertility and Development, 2016 - CSIRO Publishing
For an organ that is so critical for life in eutherian mammals, the placenta hardly gets the
attention that it deserves. The placenta does a series of remarkable things, including …
attention that it deserves. The placenta does a series of remarkable things, including …
Mapping cell-to-tissue graphs across human placenta histology whole slide images using deep learning with HAPPY
C Vanea, J Džigurski, V Rukins, O Dodi… - Nature …, 2024 - nature.com
Accurate placenta pathology assessment is essential for managing maternal and newborn
health, but the placenta's heterogeneity and temporal variability pose challenges for …
health, but the placenta's heterogeneity and temporal variability pose challenges for …
IFPA Meeting 2012 Workshop Report I: comparative placentation and animal models, advanced techniques in placental histopathology, human pluripotent stem cells …
WE Ackerman IV, AM Carter, AM De Mestre, TG Golos… - Placenta, 2013 - Elsevier
Workshops are an important part of the IFPA annual meeting as they allow for discussion of
specialized topics. At IFPA meeting 2012 there were twelve themed workshops, three of …
specialized topics. At IFPA meeting 2012 there were twelve themed workshops, three of …