Stroke is a major cause of morbidity and mortality, and activation of the immune system can
impact on stroke outcome. Although the majority of research has focused on the role of the …

Stroke represents an unresolved challenge for both developed and developing countries
and has a huge socio-economic impact. Although considerable effort has been made to limit …

The inflammatory and immunological responses play a significant role after stroke. The
innate immune activation stimulated by microglia during stroke results in the migration of …

Immunological mechanisms have come into the focus of current translational stroke
research, and the modulation of neuroinflammatory pathways has been identified as a …

Neurological disorders affect over one billion lives each year worldwide. With population
aging, this number is on the rise, making neurological disorders a major public health …

Stroke is one of the leading causes of death and disability worldwide. The long‐standing
dogma that stroke is exclusively a vascular disease has been questioned by extensive …

Increasing evidence shows that the central nervous system and the immune system interact
in complex ways, and better insight into these interactions may be relevant to the treatment …

This issue of Neurotherapeutics focuses on immunologic changes after stroke, a promising
target for stroke therapies. Stroke is a deadly and disabling disease; globally, it kills 12% of …

Over the past several decades, there have been substantial advances in our knowledge of
the pathophysiology of stroke. Understanding the benefits of timely reperfusion has led to …

Local and systemic inflammation contribute significantly to stroke risk factors as well as
determining stroke impact and outcome. Previously being considered as an immuno …