Correlation of airway obstruction and patient-reported endpoints in clinical studies

S Shingo, J Zhang, TF Reiss - European Respiratory Journal, 2001 - Eur Respiratory Soc
To establish the correlation among asthma efficacy parameters over a long period, data from
over 1500 patients in two one-year asthma clinical trials with montelukast, a Cys-LT1 …

COPD prevalence in Salzburg, Austria: results from the Burden of Obstructive Lung Disease (BOLD) study

L Schirnhofer, B Lamprecht, WM Vollmer, MJ Allison… - Chest, 2007 - Elsevier
Background: COPD is projected to be the third leading cause of death worldwide by 2020.
The Burden of Obstructive Lung Disease initiative was started to measure the prevalence of …

Comparison of existing symptom‐based questionnaires for identifying COPD in the general practice setting

CP van Schayck, RJ Halbert, RJ Nordyke… - …, 2005 - Wiley Online Library
Objective: Underdiagnosis of COPD is widespread, at least in part due to underuse of
spirometry. Symptom‐based questionnaires may be helpful as an adjunct to spirometry. The …

Smokers with airway obstruction are more likely to quit smoking

M Bednarek, D Gorecka, J Wielgomas… - Thorax, 2006 - thorax.bmj.com
Background: Chronic obstructive pulmonary disease (COPD), usually caused by tobacco
smoking, is one of the leading causes of morbidity and mortality. Smoking cessation at an …

Airflow obstruction in never smokers in five Latin American cities: the PLATINO study

R Perez-Padilla, R Fernandez, MVL Varela… - Archives of medical …, 2012 - Elsevier
BACKGROUND: Although chronic obstructive pulmonary disease (COPD) is mostly related
to tobacco smoking, a variable proportion of COPD occurs in never smokers. We …

Current clinical guideline definitions of airflow obstruction and COPD overdiagnosis in primary care

TRJ Schermer, IJM Smeele… - European …, 2008 - Eur Respiratory Soc
The aim of the present study was to establish the agreement between two recommended
definitions of airflow obstruction in symptomatic adults referred for spirometry by their …

Spirometry parameters used to define small airways obstruction in population-based studies: systematic review

B Knox-Brown, O Mulhern, J Feary, AFS Amaral - Respiratory research, 2022 - Springer
Background The assessment of small airways obstruction (SAO) using spirometry is
practiced in population-based studies. However, it is not clear what are the most used …

Development of a population-based screening questionnaire for COPD

PMA Calverley, RJ Nordyke, RJ Halbert… - COPD: Journal of …, 2005 - Taylor & Francis
COPD is commonly under-diagnosed, in part because people at risk are unaware of the
relevant risk factors and do not recognize related symptoms. Providing this information might …

The prevalence of obstructive lung disease in a general population sample: The NICECOPD study

E Murtagh, L Heaney, J Gingles, R Shepherd… - European journal of …, 2005 - Springer
Background: There are little data available on the prevalence of chronic obstructive
pulmonary disease (COPD) in the United Kingdom. The Northern Ireland Cost and …

Airflow obstruction: is it asthma or is it COPD?

P Rogliani, J Ora, E Puxeddu… - International journal of …, 2016 - Taylor & Francis
Despite the availability of guideline recommendations, diagnostic confusion between COPD
and asthma appears common, and often it is very difficult to decide whether the obstruction …