Key points Muscle fatigue can be defined as the transient decrease in maximal force that
occurs in response to muscle use. Fatigue develops because of a complex set of changes …

Muscle fatigue is a temporary decline in the force and power capacity of skeletal muscle
resulting from muscle activity. Because control of muscle is realized at the level of the motor …

Muscle fatigue has been studied with a variety approaches, tools and technologies. The foci
of these studies have ranged tremendously, from molecules to the entire organism. Single …

Much is known about the physiological impairments that can cause muscle fatigue. It is
known that fatigue can be caused by many different mechanisms, ranging from the …

Skeletal muscle fatigue is defined as the fall of force or power in response to contractile
activity. Both the mechanisms of fatigue and the modes used to elicit it vary tremendously …

Muscle fatigue encompasses a class of acute effects that impair motor performance. The
mechanisms that can produce fatigue involve all elements of the motor system, from a failure …

Recent studies suggest that the cost of muscle contraction may be reduced in old age, which
could be an important mediator of age-related differences in muscle fatigue under some …

Key points The mechanisms for the age‐related increase in fatigability during dynamic
exercise remain elusive. We tested whether age‐related impairments in muscle oxidative …

Age-related alterations of skeletal muscle are numerous and present inconsistently, and the
effect of their interaction on contractile performance can be nonintuitive. Hill-type muscle …

With aging, motoneurons and muscle tissue undergo significant changes, which influence
function in terms of strength, mobility, and overall independence. Mathematical modeling …