Age-related sarcopenia leads to muscle weakness and a concomitant increase in gait
problems and the risk of hip fracture due to falling in the elderly. Muscle weakness reduces …

The control of motor unit firing behavior during fatigue is still debated in the literature. Most
studies agree that the central nervous system increases the excitation to the motoneuron …

The present study shows a new computational FEM technique to simulate the evolution of
the mechanical response of 3D muscle models subjected to fatigue. In an attempt to obtain …

This brief review summarizes progress that has been made in the study of muscle fatigue
since a review published 15 years ago (Enoka RM, Stuart DG.. Neurobiology of muscle …

Superoxide and nitric oxide are generated by skeletal muscle, and these species are
increased by contractile activity. Mitochondria have long been assumed to play the primary …

Throughout the literature, different observations of motor unit firing behavior during muscle
fatigue have been reported and explained with varieties of conjectures. The disagreement …

The ability for muscle to repeatedly generate force is limited by fatigue. The cellular
mechanisms behind muscle fatigue are complex and potentially include breakdown at many …

Ageing is associated with a higher fatigue resistance during submaximal or maximal
fatiguing contractions. The present study aimed to investigate the contribution of the central …

When human muscle fatigues, athletic performance becomes impaired. For those
individuals suffering muscle or metabolic diseases the effects of muscle fatigue can make …

The phenomenon of neuromuscular fatigue in humans is described readily in subjective
terms and is measured objectively as an acute reduction of performance during exercise; …