Nitric oxide (NO) synthesis is markedly augmented in states of inflammation, largely due to
the expression of inducible nitric oxide synthase (iNOS). Although NO has anti-inflammatory …

Inflammation of the intestinal tract remains a very serious concern in the clinical setting.
Unfortunately, to date, the mechanisms underlying many inflammatory conditions such as …

Nitric oxide (NO) can exert both protective and proinflammatory actions in the
gastrointestinal tract. NO, formed physiologically by constitutive NO synthases, regulates …

The role of nitric oxide (NO) in inflammation represents one of the most studied yet
controversial subjects in physiology. A number of reports have demonstrated that NO …

Nitric oxide (NO.) plays a central role in the physiology of the gastrointestinal tract and its
response to critical illness. Potential sources of NO. in the gut include: intrinsic intestinal …

In recent years, nitric oxide (NO), a gas previously considered to be a potentially toxic
chemical, has been established as a diffusible universal messenger that mediates cell–cell …

Publisher Summary Local and systemic inflammation is characterized by the overproduction
of nitric oxide (NO). In most instances, the source of this NO is the inducible isoform of NO …

Almost 20 years after the identification of the biological role of nitric oxide (NO), the full
therapeutic potential of novel agents that mimic the activity of NO or interfere with its …

Nitric oxide (NO) is a pleiotropic free radical messenger molecule. There is a large body of
evidence that the inducible form of the NO synthase enzyme (iNOS) that is responsible for …

There is growing evidence that endogenous nitric oxide (NO) regulates mucosal barrier
integrity under physiological conditions and counters the increase in mucosal permeability …