Metabolic reprogramming is one of the main hallmarks of cancer cells. It refers to the
metabolic adaptations of tumor cells in response to nutrient deficiency, microenvironmental …

Cancer cells hijack metabolic pathways to support bioenergetics and biosynthetic
requirements for their uncontrolled growth. Thus, cancer can be considered as a metabolic …

Prostate cancer invokes major shifts in gene transcription and metabolic signaling to
mediate alterations in nutrient acquisition and metabolic substrate selection when compared …

Cancers must alter their metabolism to satisfy the increased demand for energy and to
produce building blocks that are required to create a rapidly growing tumor. Further, for …

Simple Summary Prostate cancer (PCa) is a hormone-dependent tumor characterized by a
highly heterogeneous clinical outcome. This neoplastic process has become a leading …

There is an urgent need for exploring new actionable targets other than androgen receptor
to improve outcome from lethal castration-resistant prostate cancer. Tumor metabolism has …

Context Neoplastic cells are characterized by metabolic alterations that sustain tumor
growth. Interventions aimed at modifying metabolic rewiring of cancer cells are currently …

Although low risk localised prostate cancer has an excellent prognosis owing to effective
treatments, such as surgery, radiation, cryosurgery and hormone therapy, metastatic …

To avoid over-or under-treatment of primary prostate tumours, there is a critical need for
molecular signatures to discriminate indolent from aggressive, lethal disease …

Prostate cancer (PCa) is the most common male malignancy and the fifth leading cause of
cancer death in men worldwide. Prostate cancer cells are characterized by a hybrid …