Connections between metabolism and epigenetics in cancers

C Thakur, F Chen - Seminars in cancer biology, 2019 - Elsevier
In the past half century, our version on cancer, from tumor initiation, growth, to metastasis, is
dominated by genetic mutation. The importance of metabolism and epigenetics was not …

Mechanisms and implications of metabolic heterogeneity in cancer

J Kim, RJ DeBerardinis - Cell metabolism, 2019 - cell.com
Tumors display reprogrammed metabolic activities that promote cancer progression. We
currently possess a limited understanding of the processes governing tumor metabolism in …

Metabolic fitness and plasticity in cancer progression

S McGuirk, Y Audet-Delage, J St-Pierre - Trends in cancer, 2020 - cell.com
Cancer cells have enhanced metabolic needs due to their rapid proliferation. Moreover,
throughout their progression from tumor precursors to metastases, cancer cells face …

Glucose metabolism in the progression of prostate cancer

F Cutruzzolà, G Giardina, M Marani, A Macone… - Frontiers in …, 2017 - frontiersin.org
Prostate cancer is one of the most common types of cancer in western country males but the
mechanisms involved in the transformation processes have not been clearly elucidated …

Metabolomics and transcriptomics profiles reveal the dysregulation of the tricarboxylic acid cycle and related mechanisms in prostate cancer

Y Shao, G Ye, S Ren, HL Piao, X Zhao… - … journal of cancer, 2018 - Wiley Online Library
Genetic alterations drive metabolic reprograming to meet increased biosynthetic precursor
and energy demands for cancer cell proliferation and survival in unfavorable environments …

[HTML][HTML] Targeting cancer metabolic vulnerabilities for advanced therapeutic efficacy

TA Muluh, X Shu, Y Ying - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cancer metabolism is how cancer cells utilize nutrients and energy to support their growth
and proliferation. Unlike normal cells, cancer cells have a unique metabolic profile that …

Metabolic changes during prostate cancer development and progression

AMK Beier, M Puhr, MB Stope, C Thomas… - Journal of cancer …, 2023 - Springer
Metabolic reprogramming has been recognised as a hallmark in solid tumours. Malignant
modification of the tumour's bioenergetics provides energy for tumour growth and …

Metabolic reprogramming of castration-resistant prostate cancer cells as a response to chemotherapy

G Petrella, F Corsi, G Ciufolini, S Germini… - Metabolites, 2022 - mdpi.com
Prostate cancer at the castration-resistant stage (CRPC) is a leading cause of death among
men due to resistance to anticancer treatments, including chemotherapy. We set up an in …

[HTML][HTML] Research into cancer metabolomics: towards a clinical metamorphosis

O Olivares, JHM Däbritz, A King, E Gottlieb… - Seminars in cell & …, 2015 - Elsevier
The acknowledgement that metabolic reprogramming is a central feature of cancer has
generated high expectations for major advances in both diagnosis and treatment of …

[图书][B] The heterogeneity of cancer metabolism

A Le - 2021 - library.oapen.org
This open access volume will introduce recent discoveries in cancer metabolism since the
publication of the first edition in 2018, providing readers with an up-to-date understanding of …