Curcumin alleviates DSS-induced colitis via inhibiting NLRP3 inflammsome activation and IL-1β production
Z Gong, S Zhao, J Zhou, J Yan, L Wang, X Du, H Li… - Molecular …, 2018 - Elsevier
Background NLRP3 inflammasome mediates IL-1β maturation, therefore plays a vital role in
the development of IBD. Curcumin is known for possessing strong anti-inflammatory …
the development of IBD. Curcumin is known for possessing strong anti-inflammatory …
Gallic acid ameliorates dextran sulfate sodium-induced ulcerative colitis in mice via inhibiting NLRP3 inflammasome
TY Yu, YM Feng, WS Kong, SN Li, XJ Sun… - Frontiers in …, 2023 - frontiersin.org
Background: Ulcerative colitis (UC) is a chronic recurrent inflammatory bowel disease (IBD).
The conventional drugs for UC may induce severe side effects. Herbal medicine is …
The conventional drugs for UC may induce severe side effects. Herbal medicine is …
Curcumin ameliorates DSS‑induced colitis in mice by regulating the Treg/Th17 signaling pathway
C Wei, JY Wang, F Xiong, BH Wu… - Molecular …, 2021 - spandidos-publications.com
Curcumin has a therapeutic effect on ulcerative colitis, but the underlying mechanism has
yet to be elucidated. The aim of the present study was to clarify the possible mechanisms …
yet to be elucidated. The aim of the present study was to clarify the possible mechanisms …
Curcumin ameliorates dextran sulfate sodium-induced experimental colitis by blocking STAT3 signaling pathway
L Liu, YL Liu, GX Liu, X Chen, K Yang, YX Yang… - International …, 2013 - Elsevier
Background and aims Although a series of studies have shown that curcumin can exert anti-
inflammatory effects in colitis by inhibiting NF-κB activation, whether these anti-inflammatory …
inflammatory effects in colitis by inhibiting NF-κB activation, whether these anti-inflammatory …
Curcumin suppresses NLRP3 inflammasome activation and protects against LPS‐induced septic shock
Z Gong, J Zhou, H Li, Y Gao, C Xu… - Molecular nutrition & …, 2015 - Wiley Online Library
Scope The NLRP3 inflammasome responds to various pathogen‐derived factors and
danger‐associated molecules, mediating IL‐1β maturation, therefore is involved in multiple …
danger‐associated molecules, mediating IL‐1β maturation, therefore is involved in multiple …
Genistein protects against DSS-induced colitis by inhibiting NLRP3 inflammasome via TGR5-cAMP signaling
Y Chen, TH Le, Q Du, Z Zhao, Y Liu, J Zou… - International …, 2019 - Elsevier
NLRP3 inflammasome has been reported to be associated with inflammatory bowel disease
including colitis due to its potential ability to induce IL-1β secretion. Emerging studies have …
including colitis due to its potential ability to induce IL-1β secretion. Emerging studies have …
Deoxycholic acid triggers NLRP3 inflammasome activation and aggravates DSS-induced colitis in mice
S Zhao, Z Gong, J Zhou, C Tian, Y Gao, C Xu… - Frontiers in …, 2016 - frontiersin.org
A westernized high-fat diet (HFD) is associated with the development of inflammatory bowel
disease (IBD). High-level fecal deoxycholic acid (DCA) caused by HFD contributes to the …
disease (IBD). High-level fecal deoxycholic acid (DCA) caused by HFD contributes to the …
Curcumin attenuates inflammation through inhibition of TLR-4 receptor in experimental colitis
A Lubbad, MA Oriowo, I Khan - Molecular and cellular biochemistry, 2009 - Springer
Curcumin, an active ingredient of Curcumin longa mediates its anti-inflammatory effects
through inhibition of NFkB. Several pathways including toll-like receptors (TLR) induce NFkB …
through inhibition of NFkB. Several pathways including toll-like receptors (TLR) induce NFkB …
Activation of cannabinoid receptor 2 ameliorates DSS-induced colitis through inhibiting NLRP3 inflammasome in macrophages
Activation of cannabinoid receptor 2 (CB2R) ameliorates inflammation, but the underlying
mechanism remains unclear. In the present study, we examined whether activation of CB2R …
mechanism remains unclear. In the present study, we examined whether activation of CB2R …
Curcumin alleviated dextran sulfate sodium‐induced colitis by regulating M1/M2 macrophage polarization and TLRs signaling pathway
ZP Kang, MX Wang, TT Wu, DY Liu… - Evidence‐Based …, 2021 - Wiley Online Library
Curcumin has shown good efficacy in mice with experimental colitis and in patients with
ulcerative colitis, but the mechanism of action through the regulation of M1/M2 macrophage …
ulcerative colitis, but the mechanism of action through the regulation of M1/M2 macrophage …