Abnormal dendritic cells (DCs) and Treg cell polarisation and dysbiosis of the intestinal flora
are typical features of the pathogenesis of inflammatory bowel disease (IBD). The natural …

Scope Curcumin is a natural polyphenol compound with multiple pharmacologic activities.
The present study aims to explore the potential therapeutic properties of curcumin on …

Activation of NLRP3 inflammasomes is crucial in the pathological process of Ulcerative
colitis (UC), which could be negatively regulated by PINK1/Parkin-driven mitophagy …

Background Sanguinarine (SAN) is an important natural anti-inflammatory constitutes and
dietary supplementation with SAN could improve the relative length of the intestine, alter gut …

Numerous therapies used for inflammatory bowel disease (IBD) target the transcription
factor NF-κB, which is involved in the production of cytokines and chemokines integral for …

Ulcerative colitis (UC) is a nonspecific inflammatory disorder characterized by oxidative and
nitrosative stress, leucocyte infiltration and up-regulation of pro-inflammatory cytokines …

Despite rapid progress in the understanding of systemic lupus erythematosus (SLE), there is
still an urgent need for novel and more effective interventions. Curcumin, a natural …

Management of inflammatory bowel disease (IBD) is a real clinical challenge. Despite
intense investigation, the mechanisms of IBD remain substantially unidentified. Some …

Formononetin is a kind of isoflavone compound and has been reported to possess anti‐
inflammatory properties. In this present study, we aimed to explore the protective effects of …

Ulcerative colitis (UC) is a chronic, relapsing, and nonspecific inflammatory bowel disease
(IBD). Phillygenin (PHI), a natural bioactive ingredient, isolated from Forsythiae Fructus …