The elevated blood levels of cholesterol and low-density lipoproteins result in
hyperlipidemia. The available expensive prophylactic treatments are kindred with severe …

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus (DM).
Schwann cell (SC) apoptosis contributes to the occurrence and development of DPN …

Background Nanostructured lipid carriers (NLCs), composed of solid and liquid lipids, and
surfactants are potentially good colloidal drug carriers. Thymoquinone is the main bioactive …

Pentazocine (PTZ), a narcotic-antagonist analgesic, has been extensively used in the
treatment of initial carcinogenic or postoperative pain. Hepatic first-pass metabolism results …

Background Genistein, one of the major isoflavones, has received great attention as a
phytoestrogen and potential cancer chemoprevention agent. However, the dissolution and …

This study aimed at carrying out a preformulation investigation of nanocochleates (NCs) and
develop andrographolide-loaded nanocochleates. Preformulation study comprised of …

Background: Nickel oxide nanoparticles (NiO-NPs) have recently been utilized in various
advanced industrial fields like lithium-ion micro batteries, nanofibers, electrochromic …

Aim: The aim of this research was to develop proniosome (niosomes) of Nigella sativa (NS)
to improve its drug release, gastrointestinal (GI) permeation and neuroprotective activity …

Background Incidence of diabetes has increased significantly worldwide over recent
decades. Our objective was to prepare and characterize a novel nano-carrier of hesperidin …

Neuropathic pain is one of the common surgical diseases, which leads to abnormal chronic
pain and pain hypersensitivity reaction. Microglia are important glial cells in the spinal cord …