Pharmacokinetics and biodistribution of thymoquinone-loaded nanostructured lipid carrier after oral and intravenous administration into rats
FH Zakarial Ansar, SY Latifah… - International journal …, 2020 - Taylor & Francis
Background Thymoquinone (TQ), an active compound isolated from Nigella sativa, has
been proven to exhibit various biological properties such as antioxidant. Although oral …
been proven to exhibit various biological properties such as antioxidant. Although oral …
Phospholipid complex-loaded self-assembled phytosomal soft nanoparticles: evidence of enhanced solubility, dissolution rate, ex vivo permeability, oral bioavailability …
DR Telange, NK Sohail, AT Hemke, PS Kharkar… - Drug Delivery and …, 2021 - Springer
In this study, self-assembled phytosomal soft nanoparticles encapsulated with phospholipid
complex (MPLC SNPs) using a combination of solvent evaporation and nanoprecipitation …
complex (MPLC SNPs) using a combination of solvent evaporation and nanoprecipitation …
Nanocarrier-mediated brain delivery of bioactives for treatment/prevention of neurodegenerative diseases
A Babazadeh, FM Vahed, SM Jafari - Journal of controlled release, 2020 - Elsevier
The treatment for brain disorders specifically neurodegenerative diseases (NDDs) has been
a main challenge in the medical field. NDDs are progressive, disabling, and non-curable …
a main challenge in the medical field. NDDs are progressive, disabling, and non-curable …
Neuroprotective potential of Honokiol in ICV-STZ induced neuroinflammation, Aβ (1− 4 2) and NF-kB expression in experimental model of rats
L Singh, S Singh - Neuroscience Letters, 2023 - Elsevier
Alzheimer's disease (AD) is a most common and prevalent age related insidious
neurological condition characterised by formation of Aβ (1− 4 2) plaques and NFT in the …
neurological condition characterised by formation of Aβ (1− 4 2) plaques and NFT in the …
Exploring lecithin/chitosan nanoparticles of ramipril for improved antihypertensive efficacy
R Chadha, S Bhandari, D Kataria… - … and Drug Delivery, 2013 - ingentaconnect.com
Ramipril, a widely used therapeutic agent used in the treatment of hypertension, exhibits
poor aqueous solubility resulting in low oral bioavailability. The present study is focused on …
poor aqueous solubility resulting in low oral bioavailability. The present study is focused on …
Neuroprotective effect of Dictyopteris divaricata extract-capped gold nanoparticles against oxygen and glucose deprivation/reoxygenation
SY Park, YJ Kim, G Park, HH Kim - Colloids and Surfaces B: Biointerfaces, 2019 - Elsevier
Combination therapy remains a promising approach to ameliorate cerebral ischemia injury.
Nevertheless, the primary mechanism of the neuroprotective properties of Dictyopteris …
Nevertheless, the primary mechanism of the neuroprotective properties of Dictyopteris …
Thymoquinone loaded solid lipid nanoparticles demonstrated antidepressant-like activity in rats via indoleamine 2, 3-dioxygenase pathway
The World Health Organization (WHO) has ranked depression the 4 th leading cause of
disability worldwide. Thymoquinone (TQ), is an active constituent of Nigella sativa having …
disability worldwide. Thymoquinone (TQ), is an active constituent of Nigella sativa having …
Compound XiongShao Capsule ameliorates streptozotocin-induced diabetic peripheral neuropathy in rats via inhibiting apoptosis, oxidative-nitrosative stress and …
M Yu, B Lei, X Song, Y Huang, X Ma, C Hao… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Compound XiongShao Capsule (CXSC), a
traditional herb formula, has been approved for using to treat diabetic peripheral neuropathy …
traditional herb formula, has been approved for using to treat diabetic peripheral neuropathy …
Enhanced Solubility and Bioavailability of Naringenin via Liposomal Nanoformulation: Preparation and In Vitro and In Vivo Evaluations
Y Wang, S Wang, CK Firempong, H Zhang, M Wang… - Aaps pharmscitech, 2017 - Springer
This study was aimed at preparing orally administered naringenin-loaded liposome for
pharmacokinetic and tissue distribution studies in animal models. The liposomal system …
pharmacokinetic and tissue distribution studies in animal models. The liposomal system …
[HTML][HTML] A protein–miRNA biomic analysis approach to explore neuroprotective potential of nobiletin in human neural progenitor cells (hNPCs)
S Jahan, UA Ansari, AK Srivastava… - Frontiers in …, 2024 - frontiersin.org
Chemical-induced neurotoxicity is increasingly recognized to accelerate the development of
neurodegenerative disorders (NDs), which pose an increasing health burden to society …
neurodegenerative disorders (NDs), which pose an increasing health burden to society …